Neutralisation of Dkk-1 protects from systemic bone loss during inflammation and reduces sclerostin expression

Gisela Ruiz Heiland; Karin Zwerina; Wolfgang Baum; Trayana Kireva; Jörg H Distler; Mario Grisanti; Frank Asuncion; Xiadong Li; Michael Ominsky; William Richards; Georg Schett; Jochen Zwerina

doi:10.1136/ard.2010.132852

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Clinical and epidemiological research

Extended report

Neutralisation of Dkk-1 protects from systemic bone loss during inflammation and reduces sclerostin expression

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	Abstract	Full	Pdf
Oct 2010	149	19	106
Nov 2010	166	56	107
Dec 2010	122	84	115
Jan 2011	67	70	74
Feb 2011	63	67	62
Mar 2011	46	52	31
Apr 2011	43	37	43
May 2011	34	37	32
Jun 2011	26	26	21
Jul 2011	41	26	38
Aug 2011	38	28	34
Sep 2011	26	18	16
Oct 2011	41	36	27
Nov 2011	70	37	41
Dec 2011	42	22	30
Jan 2012	58	21	18
Feb 2012	43	18	15
Mar 2012	47	19	13
Apr 2012	44	11	31
May 2012	57	29	15
Jun 2012	52	20	16
Jul 2012	52	23	16
Aug 2012	32	6	9
Sep 2012	25	11	10
Oct 2012	55	10	13
Nov 2012	46	15	12
Dec 2012	31	3	4
Jan 2013	59	13	16
Feb 2013	35	12	12
Mar 2013	43	9	58
Apr 2013	52	11	10
May 2013	48	7	10
Jun 2013	31	11	15
Jul 2013	24	6	12
Aug 2013	15	8	10
Sep 2013	16	3	5
Oct 2013	27	13	13
Nov 2013	21	16	11
Dec 2013	30	7	7
Jan 2014	36	10	15
Feb 2014	16	1	3
Mar 2014	41	4	8
Apr 2014	43	13	16
May 2014	31	12	11
Jun 2014	18	6	8
Jul 2014	33	7	4
Aug 2014	35	6	2
Sep 2014	37	3	8
Oct 2014	35	17	28
Nov 2014	37	4	6
Dec 2014	26	11	6
Jan 2015	24	9	8
Feb 2015	16	10	9
Mar 2015	18	9	5
Apr 2015	17	13	10
May 2015	18	3	6
Jun 2015	22	6	5
Jul 2015	15	4	1
Aug 2015	24	8	7
Sep 2015	21	5	2
Oct 2015	20	3	3
Nov 2015	21	4	3
Dec 2015	44	0	3
Jan 2016	46	5	7
Feb 2016	18	6	8
Mar 2016	28	15	10
Apr 2016	33	3	4
May 2016	18	8	9
Jun 2016	19	10	5
Jul 2016	14	1	2
Aug 2016	19	5	3
Sep 2016	17	4	0
Oct 2016	21	4	2
Nov 2016	25	16	4
Dec 2016	23	7	6
Jan 2017	19	1	2
Feb 2017	20	3	4
Mar 2017	24	2	4
Apr 2017	37	4	4
May 2017	25	6	8
Jun 2017	24	8	4
Jul 2017	69	4	3
Aug 2017	45	3	4
Sep 2017	78	7	4
Oct 2017	90	8	9
Nov 2017	77	7	2
Dec 2017	57	3	3
Jan 2018	107	11	7
Feb 2018	55	11	9
Mar 2018	51	6	3
Apr 2018	75	9	6
May 2018	57	8	5
Jun 2018	80	3	2
Jul 2018	36	1	0
Aug 2018	44	4	3
Sep 2018	41	5	6
Oct 2018	39	5	4
Nov 2018	75	4	3
Dec 2018	79	5	5
Jan 2019	73	3	2
Feb 2019	30	1	1
Mar 2019	62	10	7
Apr 2019	51	5	6
May 2019	25	3	3
Jun 2019	48	4	1
Jul 2019	20	3	2
Aug 2019	38	3	2
Sep 2019	38	4	4
Oct 2019	34	4	2
Nov 2019	37	4	4
Dec 2019	69	1	1
Jan 2020	59	4	4
Feb 2020	37	3	3
Mar 2020	58	4	4
Apr 2020	26	8	4
May 2020	42	2	3
Jun 2020	30	3	2
Jul 2020	21	1	1
Aug 2020	27	4	0
Sep 2020	66	1	1
Oct 2020	57	5	2
Nov 2020	44	3	1
Dec 2020	26	1	0
Jan 2021	47	3	3
Feb 2021	51	5	3
Mar 2021	78	8	3
Apr 2021	33	1	1
May 2021	20	6	3
Jun 2021	8	7	2
Jul 2021	5	3	3
Aug 2021	6	6	6
Sep 2021	6	5	1
Oct 2021	25	6	3
Nov 2021	60	5	0
Dec 2021	66	2	1
Jan 2022	66	11	4
Feb 2022	43	3	0
Mar 2022	62	9	1
Apr 2022	67	5	3
May 2022	87	5	1
Jun 2022	85	1	1
Jul 2022	37	4	0
Aug 2022	43	3	0
Sep 2022	86	3	0
Oct 2022	54	0	0
Nov 2022	64	4	2
Dec 2022	79	4	3
Jan 2023	54	2	0
Feb 2023	76	2	1
Mar 2023	77	2	0
Apr 2023	47	1	0
May 2023	55	4	1
Jun 2023	25	3	0
Jul 2023	47	2	0
Aug 2023	48	2	3
Sep 2023	106	4	2
Oct 2023	386	5	1
Nov 2023	525	2	0
Dec 2023	196	5	3
Jan 2024	89	0	3
Feb 2024	89	1	1
Mar 2024	74	1	2
Total	8240	1526	1590

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