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EULAR Recommendations for the management of large vessel vasculitis
  1. Chetan Mukhtyar
  1. University of Oxford, United Kingdom
    1. Loic Guillevin
    1. Univesity of Paris Descartes, France
      1. Maria C Cid
      1. Hospital Clinic, Spain
        1. Bhaskar Dasgupta
        1. Southend University Hospital NHS Foundation Trust, United Kingdom
          1. Kirsten de Groot
          1. Klinikum Offenbach, Germany
            1. Wolfgang Gross
            1. University of Schleswig-Holstein, Germany
              1. Thomas Hauser
              1. University Hospital, Switzerland
                1. Bernhard Hellmich
                1. Kreiskrankenhaus Plochingen, Germany
                  1. David Jayne
                  1. Addenbrooke's Hospital, United Kingdom
                    1. Cees GM Kallenberg
                    1. University Medical Centre Groningen, Netherlands
                      1. Peter A Merkel
                      1. Boston University School of Medicine, United States
                        1. Heiner Raspe
                        1. University of Schleswig-Holstein, Germany
                          1. Carlo Salvarani
                          1. Arcispedale S Maria Nuova, Italy
                            1. David GI Scott
                            1. Norfolk and Norwich University Hospital Trust, United Kingdom
                              1. Coen Stegeman
                              1. University Medical Centre Groningen, Netherlands
                                1. Richard Watts
                                1. Ipswich Hospital NHS Trust, United Kingdom
                                  1. Kerstin Westman
                                  1. Malmo University Hospital, Sweden
                                    1. James Witter
                                    1. United States Food and Drug Administration, United States
                                      1. Hasan Yazici
                                      1. University of Istanbul, Turkey
                                        1. Raashid Luqmani (raashid.luqmani{at}noc.anglox.nhs.uk)
                                        1. University of Oxford, United Kingdom

                                          Abstract

                                          Objectives: To develop European League Against Rheumatism (EULAR) recommendations for the management of large vessel vasculitis.

                                          Methods: An expert group (10 rheumatologists, 3 nephrologists, 2 immunolgists, 2 internists representing 8 European countries and the USA, a clinical epidemiologist and a representative from a drug regulatory agency) identified ten topics for a systematic literature search through a modified Delphi technique. In accordance with standardised EULAR operating procedures, recommendations were derived for the management of large vessel vasculitis. In the absence of evidence, recommendations were formulated on the basis of a consensus opinion.

                                          Results: Seven recommendations were made relating to the assessment, investigation and treatment of patients with large vessel vasculitis. The strength of recommendations was restricted by the low level of evidence and EULAR standardised operating procedures.

                                          Conclusions: On the basis of evidence and expert consensus, management recommendations for large vessel vasculitis have been formulated and are commended for use in everyday clinical practice.

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