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Screening for hip and knee osteoarthritis in the general population: predictive value of a questionnaire and prevalence estimates
  1. Christian H Roux (roux101fr{at}yahoo.fr)
  1. Nice University Hospital, France
    1. Alain Saraux (alain.saraux{at}chu-brest.fr)
    1. Brest University Hospital, France
      1. Bernard Mazieres (mazieres{at}cict.fr)
      1. Toulouse University Hospital, France
        1. Jacques Pouchot (jacques.pouchot{at}egp.aphp.fr)
        1. Paris University Hospital, France
          1. Johanne Morvan (johanne.morvan{at}medecine.uhp-nancy.fr)
          1. brest University Hospital, France
            1. Bruno Fautrel (bruno.fautrel{at}psl.ap-hop-paris.fr)
            1. Paris University Hospital, France
              1. Jean Testa (testa.j{at}chu-nice.fr)
              1. Nice University Hospital, France
                1. Patrice Fardellone (fardellone.patrice{at}chu-amiens.fr)
                1. Amiens University Hospital, France
                  1. Anne C Rat (rat.anne-christine{at}wanadoo.fr)
                  1. Nançy University Hospital, France
                    1. Joel Coste (coste{at}cochin.univ-paris5.fr)
                    1. Paris University Hospital, France
                      1. Francis Guillemin
                      1. Inserm CIC-EC, Nançy University, University hospital, France
                        1. Liana Euller-Ziegler (euller-ziegler.l{at}chu-nice.fr)
                        1. Nice University Hospital, France

                          Abstract

                          Objective: To study the feasibility and validity of a two-step telephone screening procedure for symptomatic knee and hip osteoarthritis (OA) in the general population.

                          Method: The screening questionnaire was based on signs and symptoms, previous diagnosis of OA, and validated OA criteria. A random sample of telephone numbers was obtained and, at each number, one individual aged 40 to 75 years was included. A physical examination and knee or hip radiographs were offered when the screen was positive. A sample of individuals with negative screens was also examined. The diagnosis of hip/knee OA was based on the American College of Rheumatology criteria for signs and symptoms and Kellgren-Lawrence radiographic stage 2 or greater. Prevalence rates were estimated with correction for the performance of the screening procedure.

                          Results: Of 1380 individuals, 479 had positive screens, among whom 109 were evaluated; Symptomatic radiographic OA was found in 50 individuals, at the knee (n=35) or hip (n=20). Corrected prevalence estimates of symptomatic OA were 7.6% [6.4-8.8] for the knee and 5% (3.9-6.1) for the hip. The screening procedure had 87% [95% confidence interval [95%CI], 79-95%] sensitivity, and 92% [95% CI: 91-93] specificity for detecting knee OA and respectively 93% [95% CI: 86-100] and 93% [95% CI: 92-94] for hip OA.

                          Conclusion: This study establishes the feasibility of a telephone screening for symptomatic knee/hip OA, which could be used for a nationwide prevalence study. Pain and previous OA diagnosis were the best items for detecting symptomatic OA.

                          • case ascertainment
                          • general population
                          • osteoarthritis
                          • prevalence
                          • telephone screening questionnaire

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