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SAT0367 Capillaroscopy patterns among systemic sclerosis patients with gastrointestinal involvement and malnutrition evaluated by self-reported questionnaires
  1. Y Yalçınkaya,
  2. Z Ertürk,
  3. AU ÜNal,
  4. S Kaymaz,
  5. P Atagündüz,
  6. H Direskeneli,
  7. N Inanç
  1. Department of Internal Medicine, Division of Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey

Abstract

Background Gastrointestinal system (GI) is commonly involved in systemic sclerosis (SSc) beginning after early stages of disease.

Objectives We aimed to investigate capillaroscopic findings among the SSc patients with GI involvement and malnutrition.

Methods GI involvement was evaluated by UCLA SCTC GIT 2.0 questionnaire (Khanna D.) (7 multi-item; reflux, distension, soilage, diarrhea, social functioning, emotional wellbeing and constipation) in SSc patients ACR/EULAR classification criteria (2013). To report the nutrition status of the patients “malnutrition universal screening tool (MUST)” (sum of the scores of body mass index, weight loss in last 3–6 months and acute disease effect) scores were calculated. Simultaneously, nail fold video-capillaroscopy (NVC) was performed in all paatients to deterimine ealy, active late scleroderma patterns (Cutalo et al.).

Results In 58 SSc patients (51 female); the mean age, duration of Raynaud's, non-Raynaud symptom (year) and follow-up (month) were 46±13, 54±50, 10±9 and 7±7, respectively. Limited cutaneous form, positive ANA and anti-Scl70, telangiectases, dysphagia, digital ulcers, lung disease were found in 40 (71%), 48 (83%) and 21 (36%), 45 (78%), 39 (67%), 33 (57%), 23 (40%) in patients, respectively. Of the NVC patterns, early was found in 16 (28%), active was in 11 (19%), late was in 28 (48%) and normal in 3 (5%). The scores of disease activity, severity and GI were shown to be higher in patients with late NVC pattern (table-1). Of the patients with MUST score of >0 (n=10), 9 had late and 1 had early NVC pattern.

Table 1.

The scores of disease activity and severity and UCLA SCTC GIT 2.0 in SSc patients

Conclusions This SSc cohort predominantly had limited cutanous disease and vascular manifestations. In patients with late scleroderma pattern, severity of GI was higher similar to disease activity and severity. Undernutrition was frequently seen in patients with late pattern. NVC might be useful to predict the severity of GI and malnutrition and allow to direct the patients to required procedures earlier.

Disclosure of Interest None declared

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