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SAT0310 Ultrasonographic scoring of the major salivary glands in sjogren's syndrome: a comparative study with disease activity indexes
  1. N İnanç1,
  2. Y Yalçınkaya1,
  3. G Mumcu2,
  4. Z Ertürk1,
  5. AU Unal1,
  6. P Atagündüz1,
  7. H Direskeneli1
  1. 1Department of Internal Medicine, Division of Rheumatology, Marmara University, School of Medicine
  2. 2Marmara University, Faculty of Dentistry, Istanbul, Turkey

Abstract

Background Sjogren's syndrome (SjS) is characterised by chronic autoimmune inflammation primarily affects the salivary and lacrimal glands. Recently, ultrasonography (USG) of major salivary glands (SG-USG) has been used to evaluate salivary glands in primary and secondary SjS.

Objectives We aimed to investigate the association between the ultrasonographic scoring of major salivary glands and disease activity indexes in patientswith primary SjS.

Methods Forty-two primary SjS patients fulfilling ACR-EULAR classification criteria (2002) were included. Disease activity indexes (Sjögren's Syndrome Patients Reported Index (ESSPRI), Visual Analogue Scale (VAS), EULAR Sjögren's Syndrome Disease Activity Index (ESSDAI)] were recorded. Major salivary glands (bilateral parotis and submandibular glands) were scored according to two different scoring system [Hocevar A. (0–48) ve Milic VD. (0–12)].

Results Demographics, clinical characteristics, disease activity indexes and SG-USG scores were summarised in table 1 and table 2.

Table 1.

Demographics and Clinical Characteristics of SjS patients (n=42)

Twenty-four (57%) and25 (60%) patients had the cut-offvalues of ≥17 (Hocevar) and ≥6 (Milic USG).The patients with the scores of ≥17 (Hocevar)were found to have higher scores of ESSPRI-total (18±5 vs 14±5, p=0,01). Hocevar and Milic USG scores were shown to be higher in anti-Ro(+) SjS patients (25±10vs14±7and7±3vs4±2, p=0,01).USG scores were not found to be associated with the scores of ESSDAI, VAS and ESSPRI items.

Conclusions Hocevar scoring system of major salivary glands was found to be related to patient reported activity in SjS. USG scores were associated with anti-Ro positivity. Evaluation of SG-USG might promote the diagnosis and follow-up of the SjS patients.

Disclosure of Interest None declared

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