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FRI0492 Obesity is highly overrepresented among swedish patients with psoriatic arthritis compared with the general population
  1. E Klingberg1,
  2. A Bilberg1,
  3. B Eliasson2,
  4. I Larsson3
  1. 1Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at University of Gothenburg
  2. 2Department of Medicine
  3. 3Department of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Göteborg, Sweden

Abstract

Background Patients with psoriatic arthritis (PsA) are at increased risk of developing cardiovascular disease.

Objectives To determine the prevalence of cardiovascular risk factors among patients with PsA followed at a Swedish Rheumatology Clinic in comparison with the general population (GP).

Methods A questionnaire including weight, height, smoking habits, hypertension, diabetes and hyperlipidemia was sent to all PsA patients registered at the Rheumatology Clinic at Sahlgrenska University Hospital, Gothenburg (N=982). Obesity was defined as body mass index (BMI) ≥30 kg/m2. Comparison with the Swedish GP was made using data from the National public health survey, “Health on equal terms”, which is sent yearly to 20 000 citizens by the Public Health Agency of Sweden.

Results 686 (70%) of the PsA patients with mean age 56±11yrs (mean: SD), 52% women, responded.Higher prevalence of self-reported obesity and several cardiovascular risk factors was found in the PsA patients compared with the GP: Obesity 28.7% [GP 15% (95% C.I. 14.5–15.9%)], current smoking 10.5% [GP 9% (8.2–9.3%)], former smoking 43.4% [GP 23% (22.3–24.0%)], never smoking 48.8% [GP 63% (61.9–63.9%)], treatment of hypertension 32.9% [GP 20% (19.6–21.2%)] and diabetes 8.3% [GP 6% (5.4–6.3%)] Treatment of hyperlipidemia was reported by 15.0% [GP no data] and overweight by 36.2% [GP 36% (34.5–36.5%)]. Data stratified by age and sex is shown in the table. (Numbers are % and 95% C.I.)

Table 1

Conclusions Obesity was highly overrepresented among the PsA patients. It is imperative to take action against weight gain in overweight patients and promote weight loss in obese patients with PsA, since obesity may be involved in the pathogenesis of the disease and may fuel disease activity.

Disclosure of Interest None declared

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