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FRI0327 Gastroscopic features and clinical characteristics in 172 cases of children with henoch-schonleinpurpura
  1. H Zeng
  1. Department of Pediatric Allergy, Immunology and Rheumatolog, Guangzhou Women and Children's Medical Center, Guangzhou, China

Abstract

Objectives To investigate gastroscopic features and explore the relationship between clinical characteristics in children with Henoch-Schonleinpuepura (HSP).

Methods To take gastroscope in 172 cases of children with HSP in our hospital and summarize the gastroscopic performance.All the case were divided into two groups by gastroduodenal mucosal bleeding or not.It was compared among the total time of abdominal pain, pain relief, hospitalization, fasting and kidney injury case in the groups.

Results Gastroscope with varying degrees of injury of 172 cases has accounted for 169 cases (98.3%).Gastroscopic mainly revealedgastroduodenal mucosal congestion, edema, rough, erosion, bleeding and ulcer, which involved 148 cases of gastric (86.0%), 158 cases of duodenal involvement (91.9%). Mucosal erosion and bleeding occurs mainly in duodenum,mostly in the descending duodenum. Duodenal bleeding accounted for 36 cases (21.8%) in the bulb and 92 cases (55.8%) in the descendant. Only five cases (2.9%) of ulcer occurred in the duodenum, where four cases of bulbar ulcer, one case of descending ulcer. Esophageal and gastric cardia mucosal just occurred in one case. There were not significant difference (P>0.05) among the time of abdominal pain, pain relief, hospitalization and fasting in the group. There was no significant difference (P>0.05) in the incidence of kidney injury between two groups of children during hospitalization.

Conclusions Gastroscopic features of HSP in children is characterized by bleeding, erosion of duodenal mucosa and occasional duodenal ulcer formation, which mostly involve the antral mucosa, rarely involving the esophagus, cardia. There was no significant difference (P>0.05) among the severity of gastroscopic performance and the time of abdominal pain, fasting,hospitalization and kidney injury of the cases during hospitalization.

Disclosure of Interest None declared

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