Article Text

OP0257-HPR Relationship between sleep disorders and disease activity in patiens with rheumatoid arthritis
  1. L Villarreal1,
  2. S Henao2,
  3. D Buitrago-Garcia3,
  4. P Santos-Moreno4
  1. 1Psychology and processes
  2. 2Patient service
  3. 3Epidemiology
  4. 4Rheumatology, Biomab, Center for Rheumatoid Arthritis, Bogota, Bogota, Colombia


Background Rheumatoid arthritis (RA) is the prevalent autoimmune inflammatory arthritis found in adults, with the worldwide prevalence ranging from 0.4% to 1.3% (1). Patients with this condition have permanent changes with different severity of arthritis deformities as well as functional disturbances; Studies had shown that every painful condition disturbs sleep, which can lead to mood and abilities disturbances (2).

Objectives The aim of this study was to describe the socio-demographic profile and sleep disorders in RA patients from a specialized RA clinic in Colombia and relationship with disease activity.

Methods A descriptive cross-sectional study was performed in a specialized clinic dedicated to care patients with rheumatoid arthritis (RA). Data was collected during our psychology consultation, through semi-structured interviews and non-probability sampling. Descriptive epidemiology was applied for continuous variables, using measures of central tendency and dispersion for categorical and qualitative variables by averages and percentages. We analyzed bivariate association with Pearson's X2.

Results We included 1398 patients attending to our psychology consultation. Mean age was 55±8. 80% were female and 20% male. Mean DAS28 was 2.6±1.3, mean HAQ was 1.6±1. 6; Patients had the disease for an average of 12 years ± 8; 41% of patients had comorbidities associated with non-autoimmune disease, 14% comorbidities related to autoimmune disease; 35% of our patients did not report other comorbidities. Most of patients were married 60%, followed by divorced 19%, single 14% and widowed 7%. Regarding occupation 33% were employees, 25% were housekeepers or retired due to age, 12% were retired due to disabilities, and 3% unemployed. Of the total population 45% had elementary school, 32% high school, 8% college education, 7% graduate education and 7% were illiterate. 17% of patients lived alone. When the psychologist asked about sleep disorders 69% reported no to have any, 25% primary insomnia, 1% hypersomnia, 3% OSAS and 2% alterations on the circadian rhythm. Disease activity was statically associated with sleep disorders (p<0.00).

Conclusions Sleep problems are an important aspect to consider in a patient with RA and are correlated to disease activity; it is important to have a multidisciplinary care team for the patient with RA, including a psychologist that can manage this kind of illness in order to improve the life quality of patients.


  1. Bautista-Molano W, Fernández-Avila D, Jiménez R, Cardozo R, Marín A, Soler MdP, et al. Epidemiological Profile of Colombian Patients With Rheumatoid Arthritis in a Specialized Care Clinic. Reumatología Clínica (English Edition). 2016;12(6):313–8.

  2. Purabdollah M, Lakdizaji S, Rahmani A, Hajalilu M, Ansarin K. Relationship between Sleep Disorders, Pain and Quality of Life in Patients with Rheumatoid Arthritis. Journal of caring sciences. 2015;4(3):233–41.


Disclosure of Interest None declared

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