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AB1101 Quality of life and work in patients with ankylosing spondylitis of working age
  1. M Parvu1,
  2. GM Muresan2,
  3. AI Cozos3,
  4. IA Biro1,
  5. HV Popoviciu1,
  6. S Szasz1,
  7. S Voidazan4
  1. 1Rheumatology, Rehabilitation, University of Medicine and Pharmacy Tg.Mures, Emergency County Hospital
  2. 2Internal Medicine
  3. 3Rheumatology, Rehabilitation, Emergency County Hospital
  4. 4Epidemiology, University of Medicine and Pharmacy, Tg.Mures, Romania


Background The assessment of the quality of life is a current research issue in patients with ankylosis spondylitis1,2. The tools for assessing the life quality, come to complete the other methods of investigation, which assess in a subjective manner the negative impact of the disease on daily activities.

Objectives The purpose of this study is to define the functional ability, the disease activity, to investigate the correlation between work and quality of life, and the impact of the quality of life in patients with AS.

Methods The study is an observational prospective study, which includes a total of 91 patients defined with AS in according to the modified New York criteria, from the Rheumatology Clinic of Targu-Mures. Data were obtained by questionnaires including several generic and disease related Quality of life tools. It includes specific tools: BASDAI (Bath Ankylosing Spondylitis Disease Activity Index); BASFI (Bath Ankylosing Spondylitis Functional Index); ASQOL (Ankylosing Spondylitis Quality of Life); and generic tools:SF-36 (Short-Form 36), Eq 5D (European-Quality of life 5 Dimensions), HAQ (Health Assessment Questionnaire and VAS (Visual Analogue Scale).

Results Out of 91 patients, 82% were males, 18% were females; mean age (years) 50,27±11,05SD; age at disease onset (years)36,20±13,51SD; duration of disease (years) 14,22±9,69SD; retiring mean age (years) 44,54±7,65SD. The mean values for BASDAI=4,23±2,21SD; BASFI=4,88±2,61SD; EQ-5D=5,71±0,20SD; EQ-VAS=64,26±18,938D; HAQ=0,747±0,51SD; SF-physical summary=33,53±8,33SD; SF-emotional summary=47,57±10,03SD; ASQOL=6,94±2,68SD. We found a positive correlation between the disease onset and retiring age p<0,0001, r=0,731a nd a negative significant correlation between BASFI and SFphysical summary (p<0,0001, r=-0,798), ASQOL and SF-emotional summary, p<0,0001, r=-0,595).

Conclusions The results showed the invalidant potential of the AS, with major impact upon the quality of life.


  1. Van der Heijde D, Landewe R. Assessment of disease activity, function and quality of life. In 1st edition Philadelfia:Mosby Elsevier;2006, 206–213.

  2. Dovard LC, McKenna SC, Meads MD et all. Translation and Validation of non English version of the ASQOL questionnaire. BioMed Central, Health and QOL outcomes, 2007, 5L7 doiL1.1186/1477–7525–5-7.


Disclosure of Interest None declared

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