Objectives The aim of this study was to explore distributions of antibodies in SLE patients in different ethnic groups in xinjiang.
Methods Data were obtained from 670 patients with SLE from Department of Rheumatology and immunology in our hospital between January 2012 and October 2016.All patients fulfilled the 1997 ACR SLE classification criteria. Data about their gender, age, ethnic groups and result of antibodies test were collected.
Results Totally 670 completed data were collected.there are 438 (65.37%) of these patients (68.22%) were Han population,136 (20.29%)were Uighur, 43 (6.42%) were Kazakh, 30 (4.48%) were hui people and 23 were other minorities live in xinjiang. The titer of ANA was higher in minorities than Han population (Z=-3.516, P<0.01). As compared with Han population, the positive rate of anti-Smith antibaodies and anti-SSA antibodies in SLE patients, significantly higher than han population (χ2=5.902, P<0.017; χ2=42.787, P<0.001, respectively). However, there are no significant different of the positive rate ofanti-SSA antibodies, anti-Scl-70 antibodies, anti-Jo-1 antibodies,anti-ds-DNA antibodies between Han population and minorities.
Conclusions Distributions of antibodies in SLE patients were different between Han population and minorities.the positive rate of anti-Smith antibaodies and anti-SSA antibodies in SLE patients were significantly higher than han population.
Disclosure of Interest None declared