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AB0560 Study on streptococcal infection relationship with henoch-schonlein purpura in children
  1. F Li1,
  2. H Zeng2
  1. 1Department of Pediatric Allergy, Immunology and Rheumatolog
  2. 2Department of Pediatric Allergy, Immunology and Rheumatology, Guangzhou Women and Children's Medical Center, Guangzhou, China

Abstract

Objectives To study hemolytic Streptococcus infection relationship with Henoch-Schonlein Purpura in children.

Methods 42 cases in children with Henoch-Schonlein Purpura (Observer Group) and healthy children in 40 cases of physical examination (the control group) for blood antistreptolysin O (ASO) detection, observation group at the same time children are divided into (belly-non-abdominal Purpura and Purpura group set and repeatedly attacks groups and the Group of non-recurrent) for statistical analysis.

Results Observation group in the blood ASO detection positive 22 cases, accounted for 52.4%; normal control group children 40 cases, blood ASO detection positive 2 cases, accounted for 5%, both comparison differences has significantly significance (χ2=22.22, p<0.01); abdominal type Purpura children with 23 cases, blood ASO detection positive 17 cases, accounted for 73.9%; non-abdominal type Purpura children with 19 cases, blood ASO detection positive 5 cases, accounted for 26.3%, both comparison differences has significantly significance (χ2=9.45, p<0.01); 14 cases in children with recurrent Henoch-Schonlein Purpura, ASO blood test positive in 12 cases, 85.7%, non-recurrent attacks of 28 cases of children with Henoch-Schonlein Purpura, ASO blood test positive in 10 cases, 35.7%, comparing the two differences are significant (χ2=9.35, p<0.01).

Conclusions Streptococcal infections may be the important factor relatated to Henoch-Schonlein Purpura in children.Purpura and Purpura of abdominal type recurrence is related with streptococcal infection, which is the great value to treatment.

Disclosure of Interest None declared

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