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AB0549 Demographic features and clinical aspects of behÇet's disease in omani patients
  1. AS Al Ghafri,
  2. H Al Wahshi
  1. Rheumatology, Royal Hospital, Muscat, Oman

Abstract

Background Behçet's disease (BD) is a chronic, relapsing, multi-system vasculitis of unknown aetiology. Few reports support the hypothesis that BD has a primarily hereditary basis. It complicated diversified clinical features predominantly involving oral and genital ulcers, ocular and cutaneous lesions. The clinical features of this disease have been described to be different according to geographical areas and gender.

Objectives The objective of the study is to explore the demographic features and clinical aspects of BD in Omani patients.

Methods 56 BD patients were recruited and clinical data parameters were recorded including age, sex, age at diagnosis, duration of symptoms till diagnosis, disease characteristics such as oral and genital ulcers, ocular manifestations, the presence of arthritis and cutaneous lesions such as papulopustular lesions and erythema nodosum. Furthermore, other systemic involvement was studied including gastrointestinal, neurological & vascular manifestations. Laboratory tests of BD and treatment used were recorded in each patient.

Results The onset was between 6–74 years with a male predominance. Oral ulcers were the most common manifestation, followed by genital ulcers, ocular lesions and arthritis. Vascular lesions and GI manifestations were less common. Cutaneous manifestations were rare in patients with BD. The frequency of neurological involvement was significantly high. There were no reported cardiac or urogenital manifestations.

Conclusions There are quite significant clinical geographical and gender differences among BD patients in which genetic and immunological factors might participate it's aetiopathogenesis.

Acknowledgements The authors thank Department of research, Oman Medical Specialty Board, Muscat, Oman, for their excellent technical assistance.

Disclosure of Interest None declared

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