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SAT0258 Assessing Myocardial Deformation of Kawasaki Patients with Speckle-Tracking Echocardiography on Long Term Follow Up
  1. S. Sahin1,
  2. R. Dedeoglu2,
  3. F. Oztunc2,
  4. K. Barut1,
  5. A. Adrovic1,
  6. S.U. Atik2,
  7. D. Cengiz3,
  8. O. Kasapcopur1
  1. 1Department of Pediatric Rheumatology
  2. 2Department of Pediatric Cardiology, Istanbul University, Cerrahpasa Medical School
  3. 3Department of Statistics, Istanbul Commerce University, Arts and Science Faculty, Istanbul, Turkey

Abstract

Background Myocardial dysfunction due to coronary arterial lesions is an important complication after Kawasaki disease in childhood (1,2). Speckle-tracking echocardiography (STE) is a recently developed technique for evaluation of myocardial deformation (3).

Objectives Our objective was to examine myocardial deformation at long term follow-up of Kawasaki patients.

Methods We assessed regional myocardial function in 32 asymptomatic Kawasaki patients and 30 age matched healthy child as control group. STE examination were recorded and the acquired raw data were saved for offline analysis The inferoseptal, anterolateral, inferior, anterior, and inferolateral (posterior) walls were investigated for longitudinal systolic peak values for strain (LV-SR) imaging.

Results Mean age was 21±12 months, mean follow up time 61 months, Left ventricular ejection fraction was 57,373±8,338 in patients and 61,100±3,804 in control group. LV-SR of Kawasaki patients at basal-inferoseptal (20,000±6,046 vs 25,200±5,074), basal-anterolateral (19,595±5,713 vs 22,733±3,494), apical-septal (23,378±5,609 vs 26,267±4,334), apical-inferior (24,054±3,696 vs 25,200±2,396) segments had lower values than control group.

Conclusions We demonstrated subclinical systolic impairment of function especially at left ascending artery territories with STE. STE has the potential to detect these subtle abnormalities, and help management during long term follow up.

  1. Printz BF, et al. Noncoronary cardiac abnormalities are associated with coronary artery dilation and with laboratory inflammatory markers in acute Kawasaki disease. Journal of the American College of Cardiology 2011;57(1): 86–92.

  2. Xu QQ, et al. Evaluation of left ventricular systolic strain in children with Kawasaki disease. Pediatric cardiology 2014;35(7): 1191–1197.

  3. Marwick TH, et al. Myocardial strain measurement with 2 dimensional speckle-tracking echocardiography: definition of normal range. JACC: Cardiovascular Imaging 2009;2(1): 80–84.

Disclosure of Interest None declared

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