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FRI0491 Etiology and Clinical Features of Uveitis in A Tertiary Center in Turkey
  1. D. Arslan Tas1,
  2. I. Turk1,
  3. N. Cuzdan Coskun1,
  4. O. Kudas1,
  5. S.O. Badak1,
  6. E. Esen2,
  7. S. Sızmaz2,
  8. N. Demircan2
  1. 1Division of Rheumatology
  2. 2Department of Ophthalmology, Çukurova University Medical Faculty, Adana, Turkey

Abstract

Background Uveitis is inflammation of uvea (iris, ciliary body, choroid). Uveitis is classified as anatomically (anterior, intermediate, posterior, panuveitis) and etiologically (infectious, non-infectious and masquerade) (1).

Objectives The aim of this study was to investigate etiology and clinical properties of uveitis in a tertiary center in Turkey.

Methods Uveitis patients who admitted to our hospital from 2013 to 2015 were evaluated. Age, gender, type of uveitis, course of the attacks and etiology were noted.

Results One hundred patients with uveitis (54% men, 46% women; age 40.01±14.1 years) were included in the study. The course of the disease was mostly acute (42%) followed by recurrent (36%) and chronic form (22%). Specific diagnosis was established in 68% of patients; whereas 32% of patients were evaluated as idiopathic. Etiology was spondiloartropathy (SpA) in 30%, Behçet's disease in 16%, infectious in 13%, connective tissue disease associated in 6%, sarcoidosis in 2% and malignancy associated uveitis in 1% of the patients. 67% of the patients had unilateral and 33% of patients had bilateral uveitis.

The characteristic properties of patients with SpA were as 56% men and 43% women; aged 43.57 ± 16.45 years. 60% of the patients with SpA had anterior, 40% had panuveitis. 46% of SpA patients had recurrent, 43% had acute and 10% had chronic uveitis. HLA B27 was positive in 50% of SpA patients. Sacroiliitis on MRI was detected in 76% of patients.

There were 32 idiopathic uveitis patients (53.1% women). Panuveitis was the most common type (37.5%) among idiopathic uveitis patients, followed by posterior uveitis (34.4%), anterior uveitis (21.9%) and intermediate uveitis (6.2%), respectively.

There were 16 patients with Behçet's disease, 62.5% of them were men. 62.5% of patients with Behçet's disease had panuveitis, 18.8% had anterior and 18.8% had posterior uveitis.

Conclusions According to the literature posterior segment involvement is a rare presentation of SpA associated uveitis (2).The results of this study are noteworthy that higher incidence of panuveitis can be seen in SpA patients.

  1. Deschenes J, Murray PI, Rao NA, Nussenblatt RB; International Uveitis Study Group. International Uveitis Study Group (IUSG): Clinical classification of uveitis. Ocul Immunol Inflamm. 2008 Jan-Feb;16(1):1–2.

  2. Ali A, Samson CM. Seronegative spondyloarthropathies and the eye. Curr Opin Ophtalmol. 2007 Nov;18(6):476–80.

Disclosure of Interest None declared

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