Pain in persons with osteoarthritis does not follow a simple, single, immutable 'natural history'. In recent years several prospective cohorts using repeated measures of patient-reported health states have matured and there has been a flurry of publications on the existence of discrete developmental trajectories of reported pain severity and other states. What does it all add up to? And what does it teach us about concepts of time, heterogeneity, and prognosis in OA? This presentation will (i) briefly introduce the rationale and assumptions underlying these methods, (ii) review published findings when applied to pain and other patient-reported health states in osteoarthritis, (iii) discuss implications of these findings for research and clinical practice, (iv) contemplate productive directions for future investigation in this field.
Disclosure of Interest None declared
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