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AB1034 The Epidemiology of The Rheumatic Manifestations Associated with Inflammatory Bowel Disease: The Preliminary Data from A Hospital-Based Cohort Study in Istanbul
  1. N. Cakir1,
  2. N. Imeryuz2,
  3. O. Atug2,
  4. H. Akin2
  1. 1Department of Rheumatology, FSM Training and Research Hospital
  2. 2Department of Gastroenterology, Medical School of Marmara University, Istanbul, Turkey

Abstract

Background Rheumatic manifestations are the most common frequent extra-intestinal manifestations (EIM) of inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and ulcerative colitis (UC), and affected 6–46% of patients1. Despite the common manifestations, data on the various ethnic populations are limited so far. Therefore, the cohort study seems a more useful tool to learn more about epidemiology and possible risk factors in the different geographical and racial groups2.

Objectives We conducted this survey to estimate the prevalences of some rheumatic manifestations associated with IBD and to study epidemiological factors of IBD in Istanbul, Turkey.

Methods The patients were enrolled from the Gastroenterological Out-patient Clinics at two Hospitals. The diagnosis was made by gastroenterologists using endoscopy and histological studies. All patients with established diagnosis of CD and UC were evaluated byr heumatolgogists for EIM. Inflammatory back pain (IBP) was defined according to Calin's criteria. The modified New York criteria were used to define ankylosing spondylitis (AS) and the European Spondyloarthropathy Study Group criteria for spondyloarthropathy (SpA).

Results A total of 223 patients diagnosed as IBD.115 ulcerative colltis (UC) and 108 Crohn'sdisease (CD).We estmated the prevalence of IBP as 21%; AS: 2.7%; sacroiliitis (SA): 5.4%; psoriasis: 1.3%; psoriatic arthritis (PsA): 0.9%; pustulosis: 0.9%; uveitis: 1.8%; polyarticular arthritis: 6%; oligoarticular arthritis: 9%; arthralgia: 27%; erythema nodosum (EN): 2.2%; recurrent oral aphthous (ROU): 18.4% (Table 1).

Table 1.

Demographic and clinical features of patients with IBD

Conclusions We concluded that AS occurs more frequently in IBD, and more often than the prevalence of AS found in the general population. There is a high prevalence of IBP in IBD. The prevalence of ROU significantly higher than in the health population3.

  1. Atzeni F, Defendenti C, DittoMC,.etal:Rheumatic manifestations in inflammatory bowel disease. Autoimmun Rev 2014;13(1):20–3.

  2. Vavricka SR, Brun L, Ballabeni P, et al.: Frequncy and risk factors for extraintestinal manifestations in the Swiss Inflammatory Bowel Disease Cohort. Am J Gastroenterol 2011;106(1): 110–9.

  3. Cakir N, Pamuk ON, Derviş E, et al.: The prevalences of some rheumatic diseases in western Turkey: Havsa study. Rheumatol Int;32(4):895–908.

Disclosure of Interest None declared

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