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AB0920 Any Predictive Factors of Therapeutic Response in Infectious Spondylitis?
  1. I. Gharsallah,
  2. R. Dhahri,
  3. N. Boussetta,
  4. R. Abid,
  5. L. Metoui,
  6. F. Laajili
  1. Internal Medicine, Military Hospital of Tunis, Tunisia, Tunis, Tunisia

Abstract

Background The aim of the present work was to describe predictive factors of good or bad outcome Infectious Spondylodiscitis according to the experience of an internal medicine department in Tunisia.

Methods Patients with SDI either confirmed or presumed and hospitalized in the internal medicine department of The Principle Military Hospital Of Tunis, Tunisia have been included in the Study.

Results Fourty-four patients met the inclusion criteria. They have been gathered over 20 years-period. They were 24 men and 20 women with an average age at 52.5 years. The diagnosis was a Tuberculous Spondylodiscitis in 22 cases (50%): among them 10 patients had a concomitant extra spinal TB. The diagnostic delay was 231 days for TB SDI and 40.5 days for SDP.

Length of hospital stay was 48.6 days (6–225 days): with a mean of 48.9 days in SDT and 45.3 days in SDP.

Regular monitoring was observed in 38 patients (17 SDP, SDT 21) with an average duration of 20 months (5–48 months). Three were lost views and three died. Evolution was considered positive if there was a clinical and biological improvement and no recurrence or death.

The analytical study objectified that existence of a immunosuppression, a longer diagnosis period, or hospitalization period and the follow-up duration were associated with a longer duration of treatment (p=0.038, p<0.001).

The absence of orthopedic complications initially or during the evolution and treatment duration were the only factors associated with good favorable change (p<0.001, p=0.004), the existence of bacteriological evidence of multifocal involvement, the presence of epidural or spinal compression showed no significant association.

Conclusions Earlier treatment with effective duration and follow up are predictive factors of favorable outcome in SDI either due to TB or regular germs.

Disclosure of Interest None declared

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