Background Juvenile Idiopathic Arthritis (JIA) is the most prevalent clinical entity between childhood rheumatic diseases. Treatment and follow-up in adulthood of patients diagnosed with JIA is not well defined, it is therefore important to define the clinical features and complications during adulthood of these patients, and thus achieve better management of the disease.
Objectives To describe the clinical features and complications in adult patients diagnosed with JIA.
Methods Cross-sectional descriptive study where the evolution of 44 patients older than 18 years diagnosed with JIA in current monitoring Services Rheumatology two tertiary hospitals is determined.
Results The current average age of the patients is 31.06 years (18–64); sex: 34 woman,10 men; average age of diagnosis was 9.9 years (1–16); mean duration of disease 21.2 years (4–53). The patient characteritics and their complications are specified in Table 1.
During follow-up the number of relevant infections occurred in 9 patients (20.5%): 4 polyarticular JIA (community-acquired pneumonia, pyelonephritis E. coli, catheter-related sepsis and repeat UTI), 2 in JIA Oligoarticular 2 with systemic JIA and another in psoriatic way; and they have required hospitalization at some point in the evolution of his illness 80% of systemic JIA, 71.4% of polyarticular JIA and 66.6% of oligoarticular JIA. Orthopedic surgery was performed in 14 patients (32%); JIA subtypes with higher number of surgeries were systemic and polyarticular RF positive. The most common surgeries: total knee and hip prosthesis. All patients have been treated with FAME (especially LFN and MTX), except for one patient with psoriatic JIA and 2 ERA B27+. Biological treatment has been used in 23 patients (52.3%): polyarticular JIA (47.6%), systemic onset JIA (100%), oligoarticular JIA (50%), arthritis-entesistis (50%). 25% received a biological; 16% received two biological and 10% three or more biological.
Conclusions Despite the small number of patients in our series, we have determined the following:1)The most frequent form of JIA on follow-up in adulthood is polyarticular (47.7%). 2)93.2% of patients received FAME treatment. 3) More than half of patients (52.3%) received treatment with biologics. 4) Relevant infections occurred in 20.5% of patients, especially in subtype polyarticular JIA. 5)The vast majority of orthopedic surgeries were performed in the pre-biological age. JIA subtypes that needed more systemic way were systemic JIA and polyarticular RF positive, the most common surgeries total hip and knee prosthesis.
Cohorte de adultos jόvenes diagnosticados con enfermedad reumática crόnica infantil. Lόpez Robledillo, J.C. Sociedad Española de Reumatología.
Disclosure of Interest None declared
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