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AB0862 Articular and Extra-Articular Damage in Patients with Juvenile Idiopathic Arthritis
  1. D. Dalia,
  2. N.E. Carmen,
  3. M.E. Aritina,
  4. P. Ileana
  1. UMF Craiova, Craiova, Romania

Abstract

Objectives The objective of this study was to asses the damage present in patients with JIA using the JADI-A and JADI-E scores, as well as their correlation to various clinical, lab and functional parameters.

Methods The study was prospective and it took place between 2009 and 2014, involving 45 Romanian patients with JIA:15 patients with the systemic form, 15 patients with the polyarticular form and 15 patients with the oligoarticular form, in which the clinical, lab and radiological factors at the onset of the disease were assessed. The reevaluation of the patients was done 3 years later, following a special protocol that included the assessment of the general state, the disease activity score (DAS 28), joint involvement, radiological modifications (according to the Dale scoring system), CHAQ, the JADI-A and JADI-E scores. The correlation between the JADI scores and other parameters was made with the help of Spearman's correlation coefficient.

Results The articular damage highlighted by the JADI-A score was present in 15 patients (33.33%). Extra-articular damage was present in 24 patients (53.33%) and the most affected form was the systemic one – 12 patients (80%). The most frequent extra-articular impairment was growth hypotrophy, which was present in 15 patients (33.33%). In the entire subject group of patients with JIA, the JADI-A score is correlated (p<0.01) with the articular score (0.62), CHAQ (0.41), and the parents (0.56) and physician (0.52) visual analogue scale. The JADI-E score is positively correlated (p<0.01) with the Steinbrocker classification (0.56), the DAS 28 score (0.53), ESR (0.3) and CHAQ (0.52).

Conclusions The articular and extra-articular damage JADI scores can represent a useful instrument for the monitoring of damage in children with JIA.

Disclosure of Interest None declared

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