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AB0837 Effects of Vitamin D Therapy on Quality of Life in Patients with fibromyalgia
  1. A. Doğru1,
  2. A. Balkarlı2,
  3. V. Cobankara3,
  4. M. Sahin1,
  5. S.E. Tunc1
  1. 1Department of Internal Medicine, Division of Rheumatology, Suleyman Demirel University, Faculty of Medicine, ısparta
  2. 2Department of Internal Medicine, Division of Rheumatology, Antalya Training and Research Hospital, Antalya
  3. 3Department of Internal Medicine, Division of Rheumatology, Pamukkale University Faculty of Medicine, Denizli, Turkey

Abstract

Background The role of vitamin D in the etiopathogenesis of fibromyalgia and non-specific musculoskeletal pain is controversial.

Objectives In our study, we aimed to investigate the effect of vitamin D therapy on quality of life in patients with fibromyalgia.

Methods 70 patients diagnosed with fibromyalgia and 65 age-sex match controls were included in the study. Patients were grouped as deficiency (<20 ng/mL), inadequacy (20–30 ng/mL) and sufficient (>30 ng/mL) according to the levels of vitamin D. Vitamin D replacement was performed for patients with deficiencies and inadequacies. Before and after vitamin D therapy, patients filled in the assessment tools.

Results Vitamin D deficiencies and inadequacies were observed in 60% of the patients (n=42). Social function, mental health and vitality areas in patients' quality of life forms were significantly lower in normal vitamin D group compared with low vitamin D group. In scales examined after Vitamin D replacement therapy, statistically significant differences were observed in the fibromyalgia impact questionnaire, Beck depression inventory, VAS and SF-36 compared to pre-treatment.

Table 1.

Baseline and post-treatment scores of Fibromyalgia Impact Questionnaire, Beck depression inventory, VAS, ASEX, sleep VAS

Table 2.

Baseline and post-treatment scores of SF-36

Conclusions Since, vitamin D deficiency seems to be linked to the pathogenesis of FMS, serum vitamin D levels should be checked routinely as a general health problem and patients should be supplemented.

Disclosure of Interest None declared

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