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AB0510 Chronic Daily Headache Deteriorates The Quality of Life in Korean Patients with Systemic Lupus Erythematosus
  1. S.-H. Kim1,
  2. H.-J. Jeong1,
  3. J.-M. Kim1,
  4. Y.S. Kim2,
  5. H.-S. Kim3,
  6. S.-J. Hong4,
  7. S.-S. Kim5,
  8. C.-N. Son1
  1. 1Department of Internal Medicine, Keimyung University School of Medicine, Dongsan Medical Center, Daegu
  2. 2Department of Internal Medicine, Chosun University Hospital, Gwangju
  3. 3Department of Internal Medicine, Soonchunhyang University Seoul Hospital
  4. 4Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul
  5. 5Department of Internal Medicine, Ulsan University School of Medicine, GangNeung Asan Hospital, Gangwon-do, Korea, Republic Of


Background Headaches is common in patients with systemic lupus erythematosus (SLE) [1]. However, the lack of specific clinical distinctions for headache in SLE has made it difficult to elucidate its pathophysiology. Chronic daily headache (CDH) is a category of headache disorders that occurs more than 15 days per month and is associated with a profound decline in the quality of life [2].

Objectives The aim of this study is to investigate the clinical characteristics of CDH in patients with SLE and their association with disease severity and the quality of life.

Methods A total of 40 consecutive patients with SLE participated in the survey. We investigated headache characteristics, visual analogue scale (VAS) for pain, and six-question headache impact test (HIT-6) to evaluate the impact of headache on the quality of life. The patients underwent required blood tests for assessment of disease activity using the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI).

Results Six patients (15%) met the criteria for CDH. The total score of HIT-6 is significantly higher in SLE patients with CDH than in those patients who suffered from headache without CDH (P=0.027). SLE patients with CDH in particular had a higher prevalence of “wish could lie down” than those who suffered from headache without CDH (P=0.017). The multivariate regression analysis indicates that the headache days per month was a predictor for headache-related disabilities.

Conclusions As far as we know, this is the first study of its kind to evaluate the correlation of CDH and the quality of life in Korean patients with SLE. CDH may deteriorate the quality of life in patients with SLE.

  1. Cuadrado MJ, Sanna G. Headache and systemic lupus erythematosus. Lupus 2003;12:943–6.

  2. Pascual J, Colas R, Castillo J. Epidemiology of chronic daily headache. Curr Pain Headache Rep 2001;5:529–36.

Disclosure of Interest None declared

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