Background Systemic Lupus Erythematosus (SLE) is an autoimmune inflammatory disease that affects various organs and systems. Cardiovascular disease is a common complication and is associated with factors inherent to the SLE and environmental factors such as overweight and poor eating habits. In addition, obesity has been speculated as a contributing factor to the onset and progression of autoimmune diseases.
Objectives Evaluate the anthropometric profile and food habit after 10 years of follow-up of a group of patients with SLE and identify possible association with chronicity index and disease activity.
Methods We evaluated 55 patients with SLE in two moments with an interval of 10 years, coming from a care referral center for SLE in Hospital de Clínicas de Porto Alegre, Brazil. For chronicity and activity was used Systemic Lupus International Collaborating Clinics (SLICC) index and Systemic Lupus Erythematosus Disease Activity Index (SLEDAI), respectively. Body Mass Index (BMI), Body Fat Percentage (BFP) and waist circumference (WC) were the anthropometric data collected in accordance with the standards of the World Health Organization (WHO). The total cholesterol, LDL, HDL and triglycerides were performed as routine care. The study was approved by the Ethics Committee of the Universidade Federal of Rio Grande do Sul (UFRGS) and all patients who agreed to participate in the study met the consent and informed.
Conclusions Our study revealed a worsening in the lipid profile and a higher concentration of abdominal fat in patients with SLE after 10 years of follow-up, although diet has remained stable. Factors related to disease or treatment may have influenced these results, but were not assessed in this study. These findings serve as a warning to us take better care of the nutritional status and lipid profile of our patients.
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Disclosure of Interest None declared
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