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AB0443 Relation Between Accumulative Damage and Disability Recogniced by The INSS* in Systemic Lupus Erythematosus Patients
  1. E. Grau Garcia1,2,
  2. M. Fernández Matilla2,
  3. G. Poveda Marín1,
  4. C. Feced Olmos1,
  5. E. Labrador Sánchez1,
  6. F.M. Ortiz Sanjuan1,
  7. N. Fernández-Llanio3,
  8. D. Hervás Marín4,
  9. V. Fornes Ferrer4,
  10. K. Arévalo Ruales1,
  11. R. Negueroles Albuixech1,
  12. J. Ivorra Cortés1,
  13. J. Fragio Gil1,
  14. I. Martínez Cordellat1,
  15. J. Valero Sanz1,
  16. I. Chalmeta Verdejo1,
  17. L. González Puig1,
  18. C. Alcañiz Escandell1,
  19. C. Nájera Herranz1,
  20. J. Castellano Cuesta3,
  21. J. Román Ivorra1
  1. 1Rheumatology Dept., HUP La Fe
  2. 2Rheumatology Research Group, IIS la Fe
  3. 3Rheumatology Dept., Hospital Arnau de Vilanova
  4. 4Biostatistics Unit, IIS La Fe, Valencia, Spain


Background Systemic Lupus Erythematosus (SLE) in a multisystemic and autoimmune disease that specially affects young women during the second and third decade, and is able to injure different organs and or systems, being the most common one affected the musculoskeletal system. Events attributed to SLE itself and other related to the disease may impact negatively in the quality of life, unemployment, disability and mortality. Recent data show that 3.8% of SLE patients have comorbidities and 59.2% of them were receiving a disability pension. In Spain, the evaluation of disability and the assignation of the mentioned pension is given by the National Social Security Institute of Spain (INSS: Instituto Nacional de la Seguridad Social).

Objectives To assess the relationship between cumulative damage regarding to the affected organ and the percentage of disability recognized by the INSS in SLE patients in Spain.

Methods Cross-sectional prospective study of SLE patients according to the SLICC-2012 criteria, from the Rheumatology Service of Arnau de Vilanova Hospital and La Fe Hospital. We collected clinical and demographic data through personal interview and the SLIC-ACR questionnaire.

Results A total of 140 patients were evaluated; of them, 95% were women with 33.39±13.63 year-old average at the diagnosis time with a 10.05±1.42 year-evolution of SLE. Clinical characteristics of each group are described in the table.

Conclusions We observed a positive correlation between percentage of recognized disability and the SLICC-ACR index score. Musculoskeletal system is, in general, the most affected one, without differences between both groups; but we found a higher proportion of damage in nervous system, renal and vasculitis in patients with a recognized disability.

Disclosure of Interest None declared

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