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Optical spectral transmission imaging (OI) measures the blood-specific absorption of light transmitted through tissue.1–5 OI of joints may measure the level of inflammation in joint diseases such as rheumatoid arthritis (RA), where the inflammatory process is associated with angiogenesis and increased blood flow.
We compared OI by Hemics Full Hand Proto with colour Doppler (CD) ultrasonography as gold standard reference for inflammation. Sixty-two patients fulfilling the 2010 European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) criteria for RA, with no significant deformation of hands or wrists and no surgery for the last 3 months, had OI performed of the wrists and all metacarpophalangeal (MCP) and proximal interphalangeal (PIP) joints. Median age was 62 years, 76% were female, median DAS28 was 3.6 and 71% were anti-CCP-positive. Fifty-eight received disease-modifying antirheumatic drugs (synthetic, biological or in combination), five of these in combination with prednisolone. Four patients did not receive antirheumatic treatment. An OI score of …