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Heterogeneity, consistency and model fit should be assessed in Bayesian network meta-analysis
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We read with deep interest the article by Wang et al1 aimed to compare the efficacy of 20 non-steroidal anti-inflammatory drugs (NSAIDs) in the short-term treatment of ankylosing spondylitis (AS). This Bayesian network meta-analysis indicated that etoricoxib was more effective in reducing pain in AS than some other NSAIDs. The result was very useful in the decision-making process, especially for pain relief in treating patients with AS. However, there are some worthwhile issues that need to be explored.
First, it is commonly agreed that meta-analysis, including network meta-analysis, should assess …