Objectives To develop evidence based points to consider on the use of imaging in the diagnosis and management of juvenile idiopathic arthritis (JIA) in clinical practice.
Methods The task force comprised an expert group of adult and paediatric rheumatologists, radiologists, and methodologists from 9 countries. Eleven key questions on the role of imaging in JIA were generated using a process of discussion and consensus. Imaging modalities included were conventional radiography (CR), ultrasound (US), magnetic resonance imaging (MRI), computed tomography (CT), scintigraphy and positron emission tomography (PET). Research evidence was searched systematically for each question using MEDLINE, EMBASE and Cochrane CENTRAL. The experts used the evidence obtained from the relevant studies to develop a set of points to consider. The task force assessed their level of agreement with each point to consider using a numerical rating scale. Quality assessment of the included studies was performed using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS)-2 tool.
Results A total of 13,277 references were identified from the search process, from which 204 studies were included in the systematic review. Nine points to consider were produced encompassing the role of imaging in making a diagnosis of JIA, detecting and monitoring inflammation and damage, predicting outcome and response to treatment, use of guided therapies, progression and remission (table). The level of evidence, grade of recommendation and level of agreement for each proposition are given in the table, and vary according to both the research evidence and expert opinion.
Conclusions Nine key points to consider for the role of imaging in the management of JIA were developed using research based evidence and expert opinion.
Disclosure of Interest None declared