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FRI0291 Decrease in Anti-Osteoporotic Drugs Prescriptions: Is there an Immediate Consequence on Hip Fracture Incidence?
  1. K. Briot1,
  2. M. Maravic2,
  3. C. Roux1
  1. 1Paris Descartes University, Cochin Hospital
  2. 2Rheumatology Department, Lariboisiere Hospital, Paris, France


Background The incidence of hip fractures decreased in France in both genders, especially in the elderly, from 2002 to 2008, in parallel with availability of bone densitometry and effective anti-osteoporotic treatments. However prescriptions of those treatments are decreasing, since 2008, and recent studies show declining of osteoporosis management after fragility fractures.

Objectives The aim of this study was to assess the incidence of hip fractures in men and women aged 60 years and over, from 2002 to 2013 in France, and to assess the potential effect of these treatment changes.

Methods Data were drawn from the French Hospital National Database which includes all hospitalizations. Hospital data for hip fractures between 2002 and 2013 were numbered and the incidence rates per 1,000,000 adjusted on age (60-74; 74-84, and ≥85 years), and gender was calculated using the data of the French population.

Results We did not observe any change in hip fracture incidence before and after 2008; The number of hip fractures increased in women (+5%; from 49,287 in 2002 to 50,215) and in men (+22%, from 12,716 to 15,482). Between 2002 and 2013, the French population increased by 21 and 29% in women and men. Thus, incidence of hip fractures over 60 years decreased by -14% in women (6,929 and 5,987 per million in 2002 and 2013, respectively) and a slight decrease of -1%was observed in men (2,344 and 2,316). An age-specific incidence decrease was also confirmed, with a decrease of -29% and -24% (p<0.00001) in elderly (≥85 years) women and men respectively.

Conclusions Over the last 12 years, the incidence of hip fractures decreased in France in women and men aged over 60 years. This decrease is particularly important in the elderly in both genders. This is observed although there is a decrease in prescription of antiosteoporotic treatments. Further studies are needed to assess potential changes in hip fractures risk factors during the last decade.

Disclosure of Interest None declared

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