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SP0217 From Theory to Practice: Case Study from the Sarah Trial
  1. M. Dritsaki
  1. University of Warwick, Coventry, United Kingdom

Abstract

The Strengthening And stretching for Rheumatoid Arthritis of the Hand (SARAH) trial was a pragmatic, multi-centre, randomised controlled trial conducted with one year follow-up across 17 National Health Service hospital trusts in England between 2009 and 2011. 490 participants with rheumatoid hand arthritis were randomised to either an exercise programme (n=246) or to usual care (n=244).

The aim of the lecture is to provide an understanding of the basic language and concepts and usefulness of economic evaluation within the clinical trials framework using the SARAH trial as a case study.

More specifically the lecture will present

  • the design of trial based economic evaluation

  • Analysis of cost (and effectiveness) data

  • Advantages and challenges of trial based economic evaluation

  • Randomised Controlled Trial (RCT)-based evidence and decision making

References

  1. Williams MA, Williamson EM, Heine PJ, Nichols V, Glover MJ, Dritsaki M, et al. Strengthening And stretching for Rheumatoid Arthritis of the Hand (SARAH). A randomised controlled trial and economic evaluation. Health Technol Assess 2015;19(19).

  2. Lamb SE, Williamson EM, Heine PJ, Adams J, Dosanjh S, Dritsaki M, Glover MJ, Lord J, McConkey C, Vnichols, Rahman A, Underwood M, Williams MA, on behalf of the SARAH Trial group (2014). Exercises to improve function of the rheumatoid hand: a randomised controlled trial The Lancet 2015;385:421-429.

Disclosure of Interest None declared

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