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SP0145 Environmental and Lifestyle Predictors for the Development of Rheumatoid Arthritis
  1. K. Costenbader
  1. Rheumatology, Brigham and Women's Hospital, Boston, United States


Genetic and environmental factors interact in the pathogenesis of autoimmune diseases, including RA. Epidemiologic research over the past few decades has identified several lifestyle and environmental factors that are related to increased risk of developing RA, including cigarette smoking, exposure to crystalline silica, obesity, and most recently dietary factors. I will review some recent research findings on the associations of each of these with risk of RA, and highlight known or suspected interactions with genetic factors.

Disclosure of Interest None declared

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