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SP0139 A Pseudomalignant Autoimmune Disease with many Different Faces
  1. P.L. Klarenbeek1,2,3
  1. 1Internal Medicine, Tergooi Hospital, Hilversum
  2. 2Clinical Immunology and Rheumatology, Academic Medical Center
  3. 3Amsterdam Rheumatology & Immunology Center, Amsterdam, Netherlands

Abstract

A number of puzzling autoimmune syndromes has recently been clustered around the same immunological feature: infiltration of tissue by IgG4 producing plasma cells. Collectively these diseases are called the IgG4 related diseases (IgG4-RD). Despite recent advances in understanding these diseases, making the diagnosis is challenging as invasive diagnostic procedures and specific tests are required. Nevertheless, diagnosing IgG4-RD is rewarding as these diseases are often mistaken for malignancy. In this presentation we will discuss several cases to demonstrate the challenges in the diagnostic process.

Disclosure of Interest None declared

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