Background Rheumatoid arthritis (RA) is associated with a high disease burden and productivity loss due to joint damage and severe functional disability. There is only limited data on productivity loss in Turkish patients with RA.
Objectives RA patients from 19 centers across Turkey underwent physical examination and completed questionnaires for global scales, HAQ-DI, EQ5D and WPS-RA. Student's t test and chi square analysis was used to compare variables. Factors associated with work productivity loss were analyzed by regression analysis.
Methods RA patients from 19 centers across Turkey underwent physical examination and completed questionnaires for global scales, HAQ-DI, EQ5D and WPS-RA. Student's t test and chi square analysis was used to compare variables. Factors associated with work productivity loss were analyzed by regression analysis.
Results 442 patients were enrolled (357 females, mean age: 51.7 years, mean disease duration 9.5 years). 91 patients (22.3%) were employed outside home. Non-working patients were older (44 vs 41, p<0.001), more likely to be female (87.1% vs 58.5%, p: <0.001). Of the remaining patients, 4.9% were unable to work due to arthritis.DMARD and biologic usage were similar in both groups (93.9% vs 95.9% and 37.4% vs 44.8%, respectively). Other features are summarized in Table below. Absenteeism and presenteeism were reported by the 23.7% and 37.6% of the patients, respectively. Higher swollen and tender joint counts,global scores and DAS28-ESR were associated with absenteeism in univariate analysis (p<0.01). Also biologic usage and lower HAQ score were related to less abstenteeism (p<0.05). In multivariate analysis, higher HAQ score (OR: 7.45, 95%CI: 1.26-44.1, p=0.027) was an independent factor for absenteeism. When assessing all RA patients, higher HAQ-DI score was associated with greater household activity impairment score in multivariate analysis (OR: 2.39, 95%CI: 1.77-3, p=0.001).
Conclusions RA has a major impact on productivity at home and at work. Higher disability score is an independent factor for both absenteeism and household activity impairment.
Acknowledgements This study was supported by an unrestricted financial grant from UCB.
Disclosure of Interest None declared