Background Poor adherence to treatment is a big common problem in Osteoporosis (OP), especially in elderly patients, and results in an increased risk of fracture
Objectives To describe the clinical characteristics of our patients with Hip fracture and evaluate their adherence to OP therapy through their attendance to scheduled medical visits
Methods Observational, retrospective, 2-year study of Hip fractures patients. We recorded: demographic and clinical data (history of fragility fractures and OP treatment previous and after hip fracture) as well as attendance at subsequent scheduled visits and the presence of cognitive deficit and dependence on others
Results 96 patients with Hip fracture were included. Demographic and clinical data are shown in Table 1:
84.4% of patients attended the second scheduled visit after hip fracture, and 54.2% and 29.2% did to first and 2nd year visits
6 patients reported fractures at the 2 year follow-up visit: 2 distal radius, 1 periprosthetic, 1 costal, 1 shoulder and 1 pelvic branches fractures.
Possible reasons recorded of loss of follow up were: death (9.4%), family decision (7.3%), intercurrence of other serious illness (4.2%) and unknown reasons (48.9%).
34.2% of females attended to the 2nd year visit and only 18'2% male did, but we didn't find a statistically significant relationship between gender and attendance at scheduled visits (p=0.217)
40.5% of patients on Zoledronic Acid completed the 2 years of follow up, as well as: 36.4% on Oral Bisphosphonates, 25% on Denosumab and 16.7% on Strontium Ranelate. The 2 patients with teriparatide also completed 2 years follow up.
34.4% of patients without cognitive deficit attended all visits, compared to 18.8% of those who had cognitive deficit (statistically significant difference; p=0.032).
Regarding dependency, 38.9% of non-dependent patients completed all visits compared to 16.7% of dependent patients (statistically significant; p=0.005).
Performing a multivariate approach using a Cox regression analysis for age, cognitive deficit and dependence we observed that the strongest factor associated with loss in follow up was dependence, followed by cognitive impairment and age
Conclusions Our experience indicate that being dependent and cognitively impaired results in lower attendance to scheduled visits, which is associated with a high risk of non-adherence to treatment
Disclosure of Interest None declared