Article Text

AB0785 Sleep Disturbances Features in Axial Spondyloarthritis: A Case-Control Study
  1. R. Dhahri1,1,
  2. I. Mahmoud,
  3. O. Saidane,
  4. I. Chrif,
  5. H. Sahli,
  6. R. Tekaya,
  7. L. Abdelmoula
  1. Rheumatology department, Charles Nicolle Hospital, TUNIS, Tunisia


Background Sleep disturbances are reported by more than 70% of patients suffering from painful disorders, including: rheumatoid arthritis (RA), osteoarthritis (OA), systemic lupus erythematosus (SLE), fibromyalgia and Sjögren's syndrome.

There is, however, a very limited research conducted on the frequency of sleep disturbances in patients with Axial Spondylarthritis (AS).

Objectives The objective of this study was, to determine the prevalence of sleep disturbances among AS patients.

Methods A cross sectional case-control study was conducted between August 2012 and August 2013 in the department of Rheumatology of Charles Nicolle Hospital. Only patients with Axial Spondyloarthritis according to the 2009 Eular criteria were included. Age- and sex-matched healthy controls were included in this case-control study. Sleep during the month preceding the evaluation was examined by MOS-SS. The association among sleep, pain, disease activity, functional status, were assessed.

Results One hundred patients with AS and 100 control group patients age and sex matched participated in this study. Patients were divided into 71 men and 29 women. Their average age is 41.72 years [16-74]. Evaluation of sleep disorders by the MOS-SS scale highlighted a sleep disturbance in 39.9% [0-100]. Daytime sleepiness was at 39% [0 to 93.33]. The respiratory impairments: snoring was present in 55% of patients with an average value of 26.2% [0-100], shortness of breath/headache upon awakening were present in 53% of patients with a mean value of 31.8% [0-100]. The average hours of sleep per night for the past four weeks was of 6.67 hours [2 -13]. Comparing to controls significant difference was noted only with snoring (p=0.028). But, considering subgroups with active (BASDAI>40), tired (EVA fatigue>50) or with significant functional impairment (BASFI>40), more remarkable differences appears.

Conclusions Although there are more sleep disorder in AS patients. This difference was significant only in subgroups with active disease or important fatigue or patients with high functional impairment.

Disclosure of Interest None declared

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