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AB0339 Stratification of Cardiovascular Risk by Framingham Score in a Mexican Mestizo Rheumatoid Arthritis Cohort
  1. D.A. Galarza-Delgado1,
  2. I.J. Colunga-Pedraza1,
  3. J.R. Azpiri2,
  4. J.A. Cardenas-de la Garza1,
  5. R. Vera-Pineda2,
  6. G. Serna-Peña3,
  7. D.O. Treviño-Montes1,
  8. M.A. Garza-Elizondo1
  1. 1Rheumatology
  2. 2Cardiology
  3. 3Internal Medicine, Hospital Universitario, Monterrey, Mexico

Abstract

Background Cardiovascular (CV) morbidity and mortality in patients with rheumatoid arthritis (RA) is higher than general population. It is the leading cause of death in this group. The traditional cardiovascular risk (CVR) factors do not fulfilled explain this increased risk. The Framingham risk score (FRS) is the main tool to stratify CVR in general population; its usefulness in RA patients remains controversial as it is believed may underestimate the CVR.

Objectives The aim of this study is to stratify CVR by FRS in a Mexican Mestizo RA cohort.

Methods A descriptive, cross sectional study was designed. This study included diagnosed RA patients (ACR criteria 1987/2010) who attended our referral center, in a period of three months (July to September 2014). Information from clinical records was collected. Patients whose clinical records did not include age, gender, diagnosis, weight, height, blood pressure, smoking and use of antihypertensive medications were excluded.

Results 204 patients with RA were included. The mean age was 54.19 years and 90.19% (n=184) were women. It was found an increased CV risk of 10% at 10 years in 45 patients (22%). The mean for this group of patients was 7.22% at 10 years.

Conclusions FRS could underestimate CVR in our population. Optimum control of CV risk factors entails a risk of 3.6%. Standard risk prediction models used in the general population do not adequately identify many RA patients with elevated CV risk. More studies are needed to evaluate the ability of FRS to predict CV risk in RA Mexican population.

References

  1. Sandoo A, et al. The relationship between cardiovascular disease risk prediction scores and vascular function and morphology in rheumatoid arthritis.Clin Exp Rheumatol. 2014 Nov-Dec;32(6):914-21.

  2. Arts EE, et al. Performance of four current risk algorithms in predicting cardiovascular events in patients with early rheumatoid arthritis. Ann Rheum Dis. 2014 Jan 3.

Disclosure of Interest None declared

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