The JAK inhibitor tofacitinib suppresses synovial JAK1-STAT signalling in rheumatoid arthritis

D L Boyle; K Soma; J Hodge; A Kavanaugh; D Mandel; P Mease; R Shurmur; A K Singhal; N Wei; S Rosengren; I Kaplan; S Krishnaswami; Z Luo; J Bradley; G S Firestein

doi:10.1136/annrheumdis-2014-206028

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The JAK inhibitor tofacitinib suppresses synovial JAK1-STAT signalling in rheumatoid arthritis

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	Abstract	Full	Pdf
Nov 2014	496	286	305
Dec 2014	375	368	203
Jan 2015	155	226	140
Feb 2015	102	122	105
Mar 2015	841	291	290
Apr 2015	135	155	85
May 2015	292	127	155
Jun 2015	105	110	82
Jul 2015	76	91	65
Aug 2015	72	92	69
Sep 2015	94	124	76
Oct 2015	53	86	40
Nov 2015	52	147	63
Dec 2015	84	78	41
Jan 2016	97	105	69
Feb 2016	60	79	59
Mar 2016	49	87	66
Apr 2016	54	66	46
May 2016	36	74	48
Jun 2016	39	50	67
Jul 2016	55	78	57
Aug 2016	46	78	52
Sep 2016	47	94	39
Oct 2016	57	82	40
Nov 2016	32	80	48
Dec 2016	27	73	40
Jan 2017	25	70	44
Feb 2017	10	83	58
Mar 2017	1	125	68
Apr 2017	4	169	78
May 2017	0	133	51
Jun 2017	41	132	54
Jul 2017	135	127	40
Aug 2017	123	116	32
Sep 2017	124	117	41
Oct 2017	134	122	45
Nov 2017	168	167	100
Dec 2017	92	90	48
Jan 2018	131	105	50
Feb 2018	126	94	50
Mar 2018	117	83	33
Apr 2018	114	96	26
May 2018	136	86	42
Jun 2018	124	92	62
Jul 2018	95	83	38
Aug 2018	100	68	38
Sep 2018	107	67	31
Oct 2018	107	73	32
Nov 2018	132	80	41
Dec 2018	112	50	25
Jan 2019	128	74	29
Feb 2019	155	86	36
Mar 2019	197	97	50
Apr 2019	147	93	38
May 2019	106	87	35
Jun 2019	119	76	30
Jul 2019	126	79	52
Aug 2019	158	97	49
Sep 2019	112	52	37
Oct 2019	139	53	54
Nov 2019	141	65	49
Dec 2019	120	71	35
Jan 2020	144	69	45
Feb 2020	124	72	51
Mar 2020	120	84	51
Apr 2020	113	75	50
May 2020	132	87	78
Jun 2020	75	61	45
Jul 2020	94	75	67
Aug 2020	86	51	50
Sep 2020	136	98	47
Oct 2020	159	95	58
Nov 2020	109	79	42
Dec 2020	147	113	50
Jan 2021	112	98	47
Feb 2021	136	98	58
Mar 2021	136	107	53
Apr 2021	153	108	81
May 2021	89	81	69
Jun 2021	61	61	61
Jul 2021	51	51	49
Aug 2021	89	88	45
Sep 2021	93	93	70
Oct 2021	99	77	72
Nov 2021	107	80	71
Dec 2021	148	124	70
Jan 2022	99	74	40
Feb 2022	103	84	38
Mar 2022	147	121	70
Apr 2022	135	129	53
May 2022	143	123	62
Jun 2022	123	105	48
Jul 2022	100	84	55
Aug 2022	95	74	44
Sep 2022	130	104	57
Oct 2022	96	78	57
Nov 2022	122	111	53
Dec 2022	81	69	31
Jan 2023	185	156	37
Feb 2023	115	97	49
Mar 2023	142	126	40
Apr 2023	74	52	39
May 2023	81	58	48
Jun 2023	92	68	37
Jul 2023	39	36	41
Aug 2023	78	54	62
Sep 2023	115	98	46
Oct 2023	179	132	40
Nov 2023	158	103	53
Dec 2023	185	122	40
Jan 2024	84	81	60
Feb 2024	138	76	37
Mar 2024	155	106	164
Total	13344	11153	6752

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