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An extra dose of rituximab improves clinical response in rheumatoid arthritis patients with initial incomplete B cell depletion: a randomised controlled trial
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    Is an extra dose of rituximab an efficacious and safe alternative to improve outcomes in rheumatoid arthritis? Comment on the article by Vital et al.
    • Markus Bredemeier, MD, MSc, PhD. Supervisor of Medical Residency Program - Rheumatology

    Dear Editor,

    I read with interest the paper by Vital el al. (1), a pilot study testing the efficacy of an extra dose of rituximab (completing 3x1000 mg over four weeks) in comparison to the standard-dose regimen (2x1000 mg) in rheumatoid arthritis (RA) patients with incomplete depletion of B cells after a first 1000 mg dose of RTX. The study represents an advance in the knowledge about the effects of rituximab, bu...

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    Conflict of Interest:
    None declared.