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We are delighted that the new cut-offs proposed for Disease Activity Score in 28 joints using CRP method (DAS28(CRP))1 have been tested and validated in another cohort.2 We hope that these validations change how DAS28(CRP) is currently being used in daily clinical practice and in clinical trials to determine low disease activity and remission. Furthermore, in our publication,1 we also proposed new cut-offs for Disease Activity Score in 28 joints using ESR method (DAS28(ESR)) that correspond to Simplified Disease Activity Index (SDAI) because we found that DAS28(ESR) underestimates the disease activity compared with SDAI.1 We hope that these new DAS28(ESR) cut-offs can also be tested in other cohorts as well.
Competing interests None.
Provenance and peer review Commissioned; internally peer reviewed.