Background Little is known regarding the patient experience regarding the impact of gout on their lives, with most published qualitative studies assessing all aspects of gout, including treatment, knowledge, disease monitoring, outcomes and patient and clinician perspective, all in single studies. While these studies have provided important information, they have only scratched the issues related to impact of gout on quality of life (QOL).
Objectives Our objective was to examine the impact of gout on quality of life and study differences by race and gender.
Methods Ten race- and sex-stratified nominal groups were conducted, oversampling for African-Americans and women with gout. Patients presented, discussed, combined and rank ordered their concerns.
Results 62 patients with mean age 65.1 years, 60% men, 64% African-American, participated in ten nominal groups: African-American men (n=23; 3 groups); African-American women (n=18; 3 groups); Caucasian men (n=15; 3 groups); and Caucasian women (n=6; 1 group). The most frequently cited highly-ranked concerns among the ten nominal groups were: (1) effect of gout flare on daily activities (n=10 groups); (2) work disability (n=8); (3) severe pain (n=8); (4) joint swelling and tenderness (n=6); (5) food restrictions (n=6); (6) medication related issues (n=6); (7) dependency on family and others (n=5); (8) emotional Impact (n=5); (9) interference with sexual function (n=4); (10) difficulty with shoes (n=4); and (11) sleep disruption (n=4). Compared to men, women ranked the following concerns high: problems with shoes (n=4 vs. 0 groups); dependency (n=3 vs. 2); and joint/limb deformity (n=2 vs. 1). Compared to Caucasians, African-Americans more often ranked the following concerns high: dietary restrictions (n=6 vs. 0 groups); severe pain (n=6 vs. 2); gout bringing the day to a “halt” (n=2 vs. 0); effect on emotional health (n=4 vs. 1); and the need for canes/crutches during flares (n=2 vs. 0).
Conclusions Gout has significant impact on patient's quality of life. There are differences in the impact of gout by race and gender.
Acknowledgements This material is the result of work supported by a grant from the Division of Rheumatology at the University of Alabama at Birmingham and the resources and use of facilities at the Birmingham VA Medical Center, Alabama, USA. J.A.S. is also supported by grants from the Agency for Health Quality and Research Center for Education and Research on Therapeutics (CERTs), National Institute of Arthritis, Musculoskeletal and Skin Diseases (NIAMS), National Institute of Aging (NIA) and National Cancer Institute (NCI).
Disclosure of Interest J. Singh Grant/research support: takeda, savient, Consultant for: Takeda, Savient, Regeneron, Allergan