In recent years a number of new imaging techniques have been developed in order to evaluate components of bone quality in-vivo, in particular advanced three-dimensional Quantitative Computer Tomography (QCT), high resolution peripheral QCT (HRpQCT) and Finite Element Analysis (FEA). There is growing evidence that spine fracture prediction can be improved with these techniques, that age-related changes are larger than for BMD and that QCT and FEA provide additional information regarding treatment effects.
HR-pQCT enables the analysis of cortical and trabecular bone properties separately and for calculating bone biomechanical competence at the distal sites of the skeleton (distal radius and distal tibia). In addition recent research expands to in-vivo assessment of fracture healing of the distal radius and of cortical bone erosions, periarticular cortical and trabecular microarchitecture, and 3D joint-space volume of the finger joints and wrists. In this presentation these novel developments will be discussed.
Disclosure of Interest None declared