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FRI0584-HPR Relationship between Pain and Functional Ability, Anxiety and Depression in Patients with Juvenile-Onset Systemic Lupus Erythematosus and Juvenile Idiopathic Arthritis
  1. S.N. Baydogan1,
  2. E. Tarakci1,
  3. O. Kasapcopur2,
  4. K. Barut2
  1. 1Faculty of Health Science, Division of Physiotherapy and Rehabilitation
  2. 2Department of Pediatric Rheumatology, Medical Faculty of Cerrahpasa, Istanbul University, İStanbul, Turkey


Background Juvenile-onset systemic lupus erythematosus (JSLE) and Juvenile idiopathic arthritis (JIA) in children and adolescents are chronic autoinflammatory affection which might occur in any joint and has a potential to cause multisystem deteriorations.

Objectives The aim of this study was to assess relationship among pain, functional ability, anxiety and depression in patients with JSLE and JIA.

Methods 16 patients with JSLE and 20 patients with JIA were enrolled in the study. The subjects were recruited in a pediatric rheumatology clinic. They were diagnosed with JSLE/JIA by a pediatric rheumatologist based on the clinical diagnostic criteria. Patients with recent diagnoses of JSLE/JIA and those with mental deficits were excluded.Visual Analog Scale (VAS) was used to evaluate pain (during rest) and well being. Functional ability was evaluated with Childhood Health Assessment Questionnaire (CHAQ). Anxiety was evaluated by The Screen for Anxiety Related Emotional Disorders (SCARED) questionnaire. Also, depressive symptoms were assessed by Children's Depression Inventory (CDI).

Results The mean age was 14.81±2.22 years and 13.90±2.12 years in patients with JSLE and JIA respectively (range 12–18 years). There were no statistically significant differences (p>0.05) in age, weight, height, body mass index, number of affected joint between patients with JSLE and JIA. Score of VAS-pain in patients with JSLE was more than in patients with JIA (p=0.01). Significant relationships were found between score of VAS-pain and score of VAS-well being (r=0.81 p=0.000) and score of SCARED (r=0.56 p=0.023) and score of CDI (r=0.57 p=0.019) in patients with JSLE. While significant relationships were found between score of CHAQ and score of VAS-well being (r=0.62. p=0.003) score of SCARED (r=0.64 p=0.002) and score of CDI (r=0.54 p=0.014) in patients with JIA.

Conclusions Increased pain provokes anxiety, and depression by decreasing well being in patients with JSLE. On the other hand, in patients with JIA reduced functional ability results increased levels of anxiety and depression symptoms. In patients with JSLE affected joint count is lower while pain severity is more when compared to patients with JIA. Therefore, we supposed that reduction of anxiety and depression symptoms is considerable in treatment of patients with JSLE and JIA.

Disclosure of Interest None declared

DOI 10.1136/annrheumdis-2014-eular.6043

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