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AB0999 Transthoracic Ultrasonography (TUS) in the Diagnosis of Pulmonary Fibrosis in Patients Diagnosed with Systemic Connective Tissue Disease
  1. N. Buda1,2,
  2. Z. Smoleńska1,
  3. W. Kosiak2,3,
  4. Z. Zdrojewski1
  1. 1Department of Internal Medicine, Connective Tissue Disease and Geriatrics, Medical University of Gdansk, Gdansk
  2. 2Polish Ultrasound Society, Warsaw
  3. 3Department of Ultrasound Diagnostic and Biopsy of the Department of Pediatrics Hematology, Oncology and Endocrinology, Medical University of Gdansk, Gdansk, Poland

Abstract

Background The aim of this study was to define the accuracy of transthoracic ultrasonography (TUS) in the diagnosis of pulmonary fibrosis.

Objectives The value of TUS in pulmonary fibrosis in a patients with connective tissue disease is not as yet established. The prospective study was conducted to analyzed ultrasound changes in patients with recognized pulmonary fibrosis by transthoracic lung sonography and compare it with high resolution computed tomography (HRCT). The aim of the study was to in determine the characteristics of ultrasound in patients with lung fibrosis.

Methods TUS was performed in 30 patients, average age 50 (SD 24), with diagnosed connective tissue disease and pulmonary fibrosis. The study group consisted of: systemic scleroderma (19), systemic vasculitides (3), mixed connective tissue disease (2), dermatomiositis (2), rheumatoid arthritis (1), ankylosing spondylitis (1), systemic lupus erythematosus (1), Sjogren's disease (1). Pulmonary fibrosis was confirmed by HRCT. The study group was compared with control group (50 subjects) with normal X-ray and no history in the direction of lung diseases.

Results In TUS has been reported: irregular pleural line - in 100% (0% in the control group, p<0.001), fragmented pleural line - in 77% (0% in the control group, p<0.001), blurred pleural line - in 52% (0% in the control group, p<0.001), thickened pleural line – in 23% (0% in the control group, p<0.001), artifacts of B lines less than three in one intercostal space - in 23% (0% in the control group, p<0.05) and more than four B lines in one intercostal space - in 69% (0% in the control group, p<0.001), and previously unrecognized artifact called the Am line- in 38% (0% in the control group, p<0.001).

Conclusions This study indicates the possibility of the diagnosis of pulmonary fibrosis using transthoracic sonography.

Disclosure of Interest None declared

DOI 10.1136/annrheumdis-2014-eular.3818

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