Objectives The aim of the study was to evaluate the femoral cartilage thicknesses of acromegalic patients using ultrasound (US).
Methods Sixty-two patients diagnosed with acromegaly (30 F, 32 M) were included. Patients' demographic and clinical characteristics were recorded. The thickness of the femoral articular cartilage was measured using a a 6-18 MHz linear probe. Measurements were performed bilaterally from three points (medial condyle, intercondylar area and lateral condyle).
Results 14 (22.5%) patients had pain in the knee joints. A significant increase in thickness of femoral articular cartilage was determined in the patients compared with the controls (all parameters, p<0.001). While measurements performed with US were correlated among themselves, the same correlation was not obtained with GH and IGF-I. Analysis of acromegaly patients as active (n=37) or inactive (n=25) revealed no significance in the thickness of the femoral cartilage.
Conclusions Acromegalic patients seem to have thicker femoral articular cartilages. The femoral cartilage was not thicker in active patients, however.
Disclosure of Interest None declared
Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.