Background The Jadas (Juvenile arthritis Disease Activity Score) is a recently developed and validated for the assessment of the activity of juvenile idiopathic arthritis (JIA) composite score it includes 4items. Articular index, physician global assessment, overall assessment relatives of patients, and the erythrocyte sedimentation rate (ESR). C-reactive protein (CRP) has been suggested as a marker of inflammation alternative to ESR
Objectives To compare the scores of JADAS ERS versus CRP in assessing the activity of JIA.
Methods Cross-sectional study including 47 patients aged less than 18 years, suffering from juvenile idiopathic arthritis, defined according to the 2001 ILAR classification. Sociodemographic parameters, clinical and para- clinical trials relating to patients were collected. 24 patients had an ESR and CRP measures. The Jadas 10-ESR and Jadas 10-CRP were used to assess disease activity. The scores of Jadas 10 ESR and CRP were calculated as a simple linear sum of their 4 components, giving a total score of 0-40, with higher scores corresponding to a severe disease activity. A descriptive and analytical statistical analysis was performed.
Results 47 patients were included with a male predominance n=28 (59.6%). the average age was 11.59 years ±3.35; 40 patients (85.1%) were scholed.The disease duration of JIA had a median of 4 years [2-6], with predominance of oligoarthritis persistent n=12 (26.7%) the median overall EVA patient was 20 [10-40]. The mean of DAS28 was 3.1±1.5 and the median of JADAS10 ESR was 11.2 [5.38], the median of JADAS10-CRP was 12 [9-15], and the correlation between Jadas 10-ESR and Jadas 10- CRP was not statistically significant; it was not found significant statistical association between JADAS10 -CRP with clinical parameters, and other means of assessment of the activity of JIA as well as different types of JIA.
Conclusions Our study showed no significant correlation between the two types of Jadas in different clinical forms. The limited number of our patients encourages us to make further larger studies to prove the superiority of one Jadas compared to another
Disclosure of Interest None declared