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AB0908 Evaluation of the Activity of Juvenile Idiopathic Arthritis by Jadas: Jadas ESR versus Jadas3
  1. M.E.I. Fanata1,2,
  2. A. Bouchra1,2,
  3. R. Samira1,2,
  4. E.B. Dalal1,2,
  5. M. Nada1,2,
  6. E. Majda1,2,
  7. S. Siham1,2,
  8. G. Sanae1,2,
  9. W. Moudjibou1,2,
  10. H.-H. Najia1,3,4
  1. 1Department of Rheumatology, El Ayachi Hospital, Ibn Sina Universitary Hospitals, Rabat-Salé
  2. 2Mohammed Vth Souissi University
  3. 3Mohammed Vth Souissi University - LIRPOS - URAC30, Rabat
  4. 4Laboratory of Biostatistics, Clinical Research and Epidemiology (LBRCE), Faculty of Medicine and Pharmacy, Rabat, Morocco

Abstract

Background The Jadas (Juvenile arthritis Disease Activity Score) is a recently developed and validated for the assessment of the activity of juvenile idiopathic arthritis (JIA), including articular index composite score, physician global assessment, evaluation overall relatives of patients and erythrocyte sedimentation rate (ESR). However, it is not always measured systematically in consultation for this JADAS3 excluding the VS has been proposed [1].

Objectives

  • – To Compare the activity of JIA by Jadas with and without VS

  • – To Explore how the exclusion of the VS Jadas (JADAS3) influence the correlation with parameters of disease activity.

Methods Cross-sectional study that included 47 patients aged under 18 years, suffering from juvenile idiopathic arthritis, defined according the ILAR 2001 classification. Sociodemographic parameters, clinical and para-clinical trials relating to patients were collected. The Jadas 10-VS and JADAS3-10 (Jadas10 without VS) were used to assess disease activity. The scores Jadas-10- VS and JADAS3 -10 were calculated as a simple linear sum of the different components, giving a total score of 0-40 for JADAS 10 –VS and to 0-30 for JADAS3-10, with highest scores corresponding to a severe disease activity. A descriptive and analytical statistical analysis was performed.

Results 47 patients were included with a male predominance n=28 (59.6%). The mean age was 11.59 years ±3.35.The disease duration of JIA had a median of 4 years [2-6], with a predominance of persistent oligoarthritis n=12 (26.7%), the median overall EVA patient was 20 [10-40] with EVA welfare of the mother who averaged 62.06±26.84. The average of DAS28 was 3.1±1.5 with a median of JADAS10-VS =12 [10-13], the median of JADAS3 -10 was 9.5 [8-10] low compared to that of JADAS10 but with a strongly positive correlation between them (p<0.001; r=0.76). Correlations between JADAS10 and JADAS3 -10 with different types of JIA were not statistically significant. Correlation between Jadas3 and clinical, biological, and evaluation of the disease was not statistically significant, but significantly with duration of evolution of the disease (p=0.04, r =0.04) the Jadas 10 was strongly correlated with DAS28 (p=0.003, r=0.48) and index limited joints (p=0.02, r=0.37).

Conclusions In our study the modified JADAS10 excluding VS -3 is highly correlated with Jadas 10.

A study on a larger scale would be desirable to show the ability of Jadas 3 to evaluate the activity of JIA.

References

  1. Flora Mcerlane et al.

Disclosure of Interest None declared

DOI 10.1136/annrheumdis-2014-eular.5262

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