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AB0883 The Factors Affecting the FAT Body Mass in Patients with Juvenile Idiopathic Arthritis
  1. A. Hari,
  2. S. Rostom,
  3. R. Lahlou,
  4. D. Khnaba,
  5. R. Bahiri,
  6. N. Hajjaj-Hassouni
  1. Rheumatology, Mohammed Vth Souissi University, El Ayachi Hospital, Ibn Sina Universitary Hospitals, Rabat-Salé, Rabat, Morocco

Abstract

Objectives To determine the factors influencing the fat body mass in patients with juvenile idiopathic arthritis.

Methods A cross sectional study in patients with juvenile idiopathic arthritis (JIA) according to the International League of Association of Rheumatology criteria was conducted. Sociodemographic parameters and clinical data related to the disease were collected.

Fat body mass was measured by dual energy X-ray absorptiometry on Lunar Prodigy machine at the full body. Disease activity of the JIA was assessed by the number of painful joints (PJ), number of swollen joints (SJ), thevisual analogic scale (VAS) of painassessed by patient (VASp) and physician (VASd), and biological parameters (ESR,CRP).

The daily food intake was assessed by a questionnaire for 7 consecutive days. Two nutritionists analyzed the diet to identify its macronutrient and oligonutriments content. Food intake was analyzed by Bilnut Version 2.01 software 1991.

Results Thirty-three patients with JIA were included. The mean age was 10±4.35 years with a male predominance (54.5%). Twenty-four percent had a systemic subtype, 27% an oligoarticular and 48% a polyarticular subtype. The median disease duration was 2 years (1-4.5). The median duration of taking corticosteroids was 3 years (1-6). The median of fat mass, PJ, SJ, VASp, VAS d, ESR and CRP were respectively 4.97g (15.96-33.45), 3 (1-9), 1 (0-3), 20 (10-50) 35 (25-50.5) 20 (10.5-40).The median content of the feed proteins, lipids and carbohydrates was respectively1.7g (0-4.75), 0.8 g (0-11.65), and 11.1g (0-32.8). There were no correlation between fat mass and disease activity of JIA parameters: PJ (r=0.27, p=0.20), SJ (r=0.29, p=0.18), VASp (r=0.06, p=0.76), VAS d (r=0.13, p=0.53), ESR (r=0.18, p=0.4), CRP (r=0.24, p=0.28). There was a positive correlation between fat mass and the cumulative dose of corticosteroids (r=0.55, p=0.04) whereas there was no correlation with duration of its use (r=0.24, p=0.41). There were no correlation between the mass fat and the protein content of feed (r=0.13, p=0.54), fat content (r=0.15, p=0.5) and carbohydrates (r=0.07, p=0.73).

Conclusions This study suggests that fat mass was not correlated with the activity of JIA or the content of macronutrients in the diet but it was associated with the cumulative dose of corticosteroids parameters.

Disclosure of Interest None declared

DOI 10.1136/annrheumdis-2014-eular.5276

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