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AB0882 To Determine the Factors Influencing the Lean Body Mass in Patients with Juvenile Idiopathic Arthritis
  1. A. Hari,
  2. S. Rostom,
  3. R. Lahlou,
  4. D. Khnaba,
  5. R. Bahiri,
  6. N. Hajjaj-Hassouni
  1. Rheumatology, Mohammed Vth Souissi University, Rabat, El Ayachi Hospital, Ibn Sina Universitary Hospitals, Rabat-Salé, Fez, Morocco

Abstract

Objectives To determine the factors influencing the lean body mass in patients with juvenile idiopathic arthritis.

Methods A cross sectional study in patients with juvenile idiopathic arthritis (JIA) according to the International League of Association of Rheumatology criteria was conducted. Sociodemographic parameters and clinical data related to the disease were collected.

Lean body mass was measured by dual energy X-ray absorptiometry on Lunar Prodigy machine at the full body. Disease activity of the JIA was assessed by the number of painful joints (PJ), number of swollen joints (SJ), thevisual analogic scale (VAS) painassessed by patient (VASp) and physician (VASd), and biological parameters (ESR,CRP).

The daily food intake was assessed by a questionnaire for 7 consecutive days. Two nutritionists analyzed the diet to identify its macronutrient and oligonutriments content. Food intake was analyzed by Bilnut Version 2.01 software 1991, which was validated.

Results Thirty-three patients with JIA were included. The mean age was 10±4.35 years with a male predominance (54.5%). Twenty-four percent had a systemic form, 27% an oligoarticular and 48% a polyarticular form. The median disease duration was 2 years (1-4.5). The median duration of taking corticosteroids was 3 years (1-6).The median of lean mass, PJ, SJ, VASp, VAS d, ESR and CRP were respectively 20.5g (15.96-33.45), 3 (1-9), 1 (0-3), 20 (10-50) 35 (25-50.5) 20 (10.5-40).The median content of the feed proteins, lipids and carbohydrates was respectively1.7g (0-4.75), 0.8 g (0-11.65), and 11.1g (0-32.8).There was no correlation between lean mass and JIA disease activity parameters: PJ (r=0.06, p=0.7), SJ (r=0.25, p=0.23), VASp (r=0.16, p=0.46), VASd (r=0.02, p=0.9), ESR (r=0.13, p=0.54), CRP (r=0.10, p=0.64).There was no correlation between lean body mass and the cumulative duration and taking of corticosteroids with respectively (r =0.15, p=0.61) dose (r=0.28, p=0.33).There was no correlation between lean mass and content of feed on protein (r=0.17, p=0.41), fat (r=0.14, p=0.32), or carbohydrate (r=0.32, p=0.12).

Conclusions This study suggests that there was no correlation between lean body mass, disease activity parameters, and taking corticosteroids in children with JIA.

Disclosure of Interest None declared

DOI 10.1136/annrheumdis-2014-eular.5267

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