Background Fibromyalgia syndrome is a chronic disease with unknown etiology, characterized by widespread pain. QT dispersion represents a general repolarization abnormality and autonomic dysfunction. Longer QT dispersion is associated with higher risk of ventricular arrhythmias, cardiac events and mortality. P wave dispersion is a simple and useful parameter for the prediction of atrial arrhythmias. QT and P wave dispersions were investigated in several chronic inflammatory disorders such as rheumatoid arthritis, systemic lupus erythematosus, Behçet's disease, and ankylosing spondylitis.
Objectives The aim of the present study was to evaluate QT dispersion and P wave dispersions in patients with fibromyalgia.
Methods The study involved 48 fibromyalgia patients fulfilled the established criteria and 29 healthy controls (HC). Standard 12-lead electrocardiogram was performed on all participants. QT dispersion was defined as the difference between the longest and the shortest QT intervals. Similarly, the differences between the shortest and the longest P wave were defined as P wave dispersion.
Results The QT dispersion was shorter in the fibromyalgia group, when compared with the HC group (p<0.001, Table). In terms of P wave dispersion value, there was no significant difference between the fibromyalgia and HC groups (p=0.088, Table).
Conclusions Longer QT and P wave dispersions could not be observed in patients with fibromyalgia in our study. Therefore, it may be concluded that fibromyalgia have not the increased risk of atrial and/or ventricular arrhythmias.
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Disclosure of Interest None declared