Background Sleep disturbance in patients with Ankylosing Spondylarthritis (AS) seems to be multifactorial. In fact inflammatory pain, depression and anxiety could have a negative impact on sleep quality in patients with AS.

Objectives The aim of this study was to evaluate sleep quality and its relationship with psychological features and fatigue in patients with AS.

Methods We conduct a cross sectional prospective study including patients with AS fulfilling the New York modified criteria. The MOS sleep Questionnaire was used for the assessment of sleep disturbance. It is a 12-item questionnaire exploring 6 domains of sleep: sleep adequacy, sleep disturbance, sleep quantity, daytime sleepiness, and shortness of breath or headache. It leads to two sleep problem indexes (SP1 and SP2). Beck depression and anxiety inventories (BDI, BAI) were used to evaluate psychological features and Chalder scale was used to evaluate the fatigue.

Results Fifty patients with AS patients were included. The mean age was 42±12.1 years (range 18 to 65) with a male to ratio female about 3.5. The mean VAS for joint pain was 49.85±25.17 [range 0.5 to 90]. The mean BDI score was 16.2±11.8 [0-43] and the mean BAI score was 14.7±10.5 [0-36]. The mean somatic fatigue score was 5.9±2.3 [0-8] and the mean mental fatigue score was 1.8±2 [0-6].The results of the MOS sleep questionnaire and the correlations of its items with BDI, BAI and Chalder scale was presented in Table 1.

Conclusions Our study showed that the poor sleep quality in AS is highly associated with depression anxiety and fatigue except for snoring which is related to BMI.

Disclosure of Interest None declared

DOI 10.1136/annrheumdis-2014-eular.6033