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AB0684 Proposed criteria for activity, damage and impact of juvenile idiopathic arthritis associated uveitis: consensus effort from the multinational interdisciplinary working group for uveitis in childhood (miwguc)
  1. I. Foeldvari1,
  2. A. Heiligenhaus2,
  3. C. Edelstein3,
  4. J. Anton4,
  5. T. Saurenmann5,
  6. B. Bodaghi6,
  7. K. Kotaniem7,
  8. S. Nielsen8,
  9. L. Sandfeld9,
  10. G. Brumm10,
  11. E. Rabinovitch11,
  12. A. Ramanan12
  1. 1Pediatric Rheumatology, Hamburger Zentrum Kinder- Und Jugendrheumatologie, Hamburg
  2. 2Augenklinik, Münster, Germany
  3. 3Opthalmology, Childrens Hospital, London, United Kingdom
  4. 4Pediatric Rheumatology, University Childrens Hospital, Barcelona, Spain
  5. 5Am Schönklinik Hamburg, University Childrens Hospital, Zürich, Switzerland
  6. 6Opthalmology, University, Paris, France
  7. 7Opthalmology, University, Helsinki, Finland
  8. 8Opthalmology, University Childrens Hospital
  9. 9Opthalmology, University, Copenhagen, Denmark
  10. 10Opthalmology, University, Hamburg, Germany
  11. 11Pediatric Rheumatology, University Childrens Hospital, Durham
  12. 12Pediatric Rheumatology, University Childrens Hospital, Bristol, United States

Abstract

Background Uveitis is the most common extraartricular manifesation of juvenile idiopathic arthritis (JIA). Uveitis, a potentially blinding disorder, is present in approx 10-18% of JIA patients, with a wide spectrum of presentations. Despite advances in treatment of childhood arthritis there are no definitions for assessment of activity, damage and impact of JIA associated uveitis.

Objectives The purpose of our efforts was to develop and gain consensus on such definitions

Methods At the second consensus meeting of the MIWGUC group, using a Delphi method we developed definitions for activity, damage and impact of disease based on already published outcome measures [1].

Conclusions We will validate these proposed definitions propsectively in a JIA associated uveitis cohort. Based on the results, we will weight these measures to develop an overall scoring system.

  1. Heiligenhaus, A., et al., Proposed outcome measures for prospective clinical trials in juvenile idiopathic arthritis-associated uveitis: A consensus effort from the multinational interdisciplinary working group for uveitis in childhood (MIWGUC). Arthritis Care Res (Hoboken), 2012.

Disclosure of Interest None Declared

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