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AB0194 Scottish early rheumatoid arthritis (sera) at nhs highland - a multi centre scottish project aiming to establish a clinical database and biorepository of newly diagnosed undifferentiated arthritis (ua) and rheumatoid arthritis (ra) patients
  1. S. Ross1
  1. 1NHS Highland, Inverness, United Kingdom


Background Depression and anxiety can be prevalent in newly diagnosed UA & RA patients and can be related to either environmental, social or for health reasons. The SERA study has enabled an in depth investigation of 31 patients with RA/UA to find out whether symptoms of depression and anxiety are alleviated with a reduction in disease progression as illustrated by disease activity score (DAS28). It also considers how other factors such as body mass index (BMI), HAQ, smoking, age and sex may have an influence on the above

Objectives To determine the relationship between anxiety, depression and DAS28

To determine the relationship between anxiety, depression, DAS28 and other influencing factors. (Influencing factors used were sex of patient, age of patient, body mass index (BMI) and smoking status at baseline)

Methods Newly diagnosed UA and RA patients were asked to complete a Hospital Anxiety & Depression (HAD) questionnaire and a Health Analysis Questionnaire (HAQ) at their baseline visit. They were then asked to do the same questionnaires at six months. All data was then entered on to the e-crf.

Results Trend analysis of the data appears to suggest a definite link between anxiety, depression and DAS improvement. The poster will discuss this matter and the other variables that play in specific detail.

Conclusions There may be a positive relationship between an improvement of a patietns DAS score and an improvement in their anxiety and depression status

Acknowledgements With kind permission from Chief Investigator of SERA study Dr D. Porter, Consultant Rheumatologist

Disclosure of Interest None Declared

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